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2.5.1.42: geranylgeranylglycerol-phosphate geranylgeranyltransferase

This is an abbreviated version!
For detailed information about geranylgeranylglycerol-phosphate geranylgeranyltransferase, go to the full flat file.

Word Map on EC 2.5.1.42

Reaction

geranylgeranyl diphosphate
+
3-(O-geranylgeranyl)-sn-glycerol 1-phosphate
=
diphosphate
 +
2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

Synonyms

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, geranylgeranyltransferase II, geranylgeranyltransferase, geranylgeranyloxyglycerol phosphate, UbiA-2 protein

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.42 geranylgeranylglycerol-phosphate geranylgeranyltransferase

Metals Ions

Metals Ions on EC 2.5.1.42 - geranylgeranylglycerol-phosphate geranylgeranyltransferase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
divalent metal ion required, optimal activity with 10 mM Mg2+. 40% of maximal activity is obtrained with 10 mM Ca2+. 1 mM Ca2+ hardly activates
Mg2+
requirement of a divalent metal ion for activity. 1 mM Mg2+ gives 40% of the activity with 10 mM Mg2+
Mn2+
divalent metal ion required, optimal activity with 10 mM Mg2+. 10 mM Mn2+ leads to severely decreased activity
Zn2+
divalent metal ion required, optimal activity with 10 mM Mg2+. 10 mM Zn2+ leads to severely decreased activity. 1 mM Zn2+ hardly activates