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EC 2.1.2.7 Details

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EC number

2.1.2.7

Accepted name

D-alanine 2-hydroxymethyltransferase

Reaction

5,10-methylenetetrahydrofolate + D-alanine + H₂O = tetrahydrofolate + 2-methylserine

Other name(s)

2-methylserine hydroxymethyltransferase

Systematic name

5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase

CAS registry number

9075-76-7

Comment

Also acts on 2-hydroxymethylserine.

History

created 1972

EC Tree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.2 Acting on the aldehyde or oxo group of donors

1.3 Acting on the CH-CH group of donors

1.4 Acting on the CH-NH₂ group of donors

1.5 Acting on the CH-NH group of donors

1.6 Acting on NADH or NADPH

1.7 Acting on other nitrogenous compounds as donors

1.8 Acting on a sulfur group of donors

1.9 Acting on a heme group of donors

1.10 Acting on diphenols and related substances as donors

1.11 Acting on a peroxide as acceptor

1.12 Acting on hydrogen as donor

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.15 Acting on superoxide as acceptor

1.16 Oxidizing metal ions

1.17 Acting on CH or CH₂ groups

1.18 Acting on iron-sulfur proteins as donors

1.19 Acting on reduced flavodoxin as donor

1.20 Acting on phosphorus or arsenic in donors

1.21 Catalysing the reaction X-H + Y-H = X-Y

1.22 Acting on halogen in donors

1.23 Reducing C-O-C group as acceptor

1.97 Other oxidoreductases

1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.2 Hydroxymethyl-, formyl- and related transferases

2.1.2.1 glycine hydroxymethyltransferase

2.1.2.2 phosphoribosylglycinamide formyltransferase 1

2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

2.1.2.4 glycine formimidoyltransferase

2.1.2.5 glutamate formimidoyltransferase

2.1.2.6 created 1965, deleted 1984

2.1.2.7 D-alanine 2-hydroxymethyltransferase

2.1.2.8 deoxycytidylate 5-hydroxymethyltransferase

2.1.2.9 methionyl-tRNA formyltransferase

2.1.2.10 aminomethyltransferase

2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase

2.1.2.12 created 1983, deleted 1984

2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase

2.1.2.14 GDP-perosamine N-formyltransferase

2.1.3 Carboxy- and carbamoyltransferases

2.1.4 Amidinotransferases

2.1.5 Methylenetransferases

2.2 Transferring aldehyde or ketonic groups

2.3 Acyltransferases

2.4 Glycosyltransferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.6 Transferring nitrogenous groups

2.7 Transferring phosphorus-containing groups

2.8 Transferring sulfur-containing groups

2.9 Transferring selenium-containing groups

2.10 Transferring molybdenum- or tungsten-containing groups

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Release 2023.1 (January 2023)