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Information on EC 1.3.1.104 - enoyl-[acyl-carrier-protein] reductase (NADPH)

for references in articles please use BRENDA:EC1.3.1.104

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IUBMB Comments

The enzyme completes each cycle of fatty acid elongation by catalysing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to the acyl-carrier protein, in an NADPH-dependent manner. This entry stands for enzymes whose stereo-specificity with respect to NADP+ is not known. [cf. EC 1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific), EC 1.3.1.10, enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) and EC 1.3.1.9, enoyl-[acyl-carrier-protein] reductase (NADH)].

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
enoyl-ACP reductase, enoyl-acyl carrier protein reductase, enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate) reductase, ENR, ETR1, FabI, FabL, Fabl2, JamJ, NADPH 2-enoyl Co A reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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