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Information on EC 1.3.1.121 - 4-amino-4-deoxyprephenate dehydrogenase

for references in articles please use BRENDA:EC1.3.1.121
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IUBMB Comments
The enzyme, characterized from the bacteria Streptomyces venezuelae and Streptomyces pristinaespiralis, participates in the biosynthesis of the antibiotics chloramphenicol and pristinamycin IA, respectively. cf. EC 1.3.1.12, prephenate dehydrogenase.
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The enzyme appears in viruses and cellular organisms
Synonyms
cmlC, papC, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-amino-4-deoxyprephenate + NAD+ = 3-(4-aminophenyl)pyruvate + CO2 + NADH + H+
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