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Information on EC 2.8.4.6 - S-methyl-1-thioxylulose 5-phosphate methylthiotransferase

for references in articles please use BRENDA:EC2.8.4.6

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IUBMB Comments

The enzyme, characterized from the bacterium Rhodospirillum rubrum, belongs to the cupin superfamily and contains a manganese ion. It participates in an anaerobic salvage pathway that restores methionine from S-methyl-5'-thioadenosine. The enzyme was assayed in vitro using L-dithiothreitol instead of glutathione.

The expected taxonomic range for this enzyme is: Rhodospirillum rubrum

Synonyms
mtxu 5-p methylsulfurylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-methyl-1-thio-D-xylulose 5-phosphate + glutathione = 1-deoxy-D-xylulose 5-phosphate + S-(methylsulfanyl)glutathione
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
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