Reference on EC 4.2.2.5 - chondroitin AC lyase
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Hascall, V.C.; Riolo, R.L.; Hayward, J.; Reynolds, C.C.
Treatment of bovine nasal cartilage proteoglycan with chondroitinases from Flavobacterium heparinum and Proteus vulgaris
J. Biol. Chem.
247
4521-4528
1972
Pedobacter heparinus
Klingbeil, U.; Klein, U.; von Figura, K.
Action of chondroitinases ABC and AC on chondroitin 4-sulfate-oligosaccharides with terminal N-acetylgalactosaminitol residues
Hoppe-Seyler's Z. Physiol. Chem.
359
765-767
1978
Proteus vulgaris
Aguiarand, J.A.K.; Michelacci, Y.M.
Preparation and purification of Flavobacterium heparinum chondroitinases AC and B by hydrophobic interaction chromatography
Braz. J. Med. Biol. Res.
32
545-550
1999
Pedobacter heparinus
Michelacci, Y.M.; Dietrich, C.P.
A comparative study between a chondroitinase B and a chondroitinase AC from Flavobacterium heparinum: Isolation of a chondroitinase AC-susceptible dodecasaccharide from chondroitin sulphate B
Biochem. J.
151
121-129
1975
Pedobacter heparinus
Hiyama, K.; Okada, S.
Action of chondroitinases. I. The mode of action of two chondroitinase-AC preparations of different origin
J. Biochem.
80
1201-1207
1976
Paenarthrobacter aurescens, Pedobacter heparinus
Hiyama, K.; Okada, S.
Multiple forms of chondroitinase AC from Arthrobacter aurescens
Agric. Biol. Chem.
41
1279-1286
1977
Paenarthrobacter aurescens
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Hiyama, K.; Okada, S.
Action of chondroitinases. III. Ionic strength effects and kinetics in the action of chondroitinase AC
J. Biochem.
82
429-436
1977
Paenarthrobacter aurescens, Pedobacter heparinus
Ulrich, H.P.; Klein, U.; von Figura, K.
Degradation of even-numbered reduced and non-reduced hyaluronate oligosaccharides with D-glucuronic acid or N-acetyl-D-glucosamine as non-reducing terminal by chondroitin ABC and AC lyases
Hoppe-Seyler's Z. Physiol. Chem.
360
1457-1463
1979
Paenarthrobacter aurescens
Hiyama, K.; Okada, S.
Amino acid composition and physiochemical characterization of chondroitinase from Arthrobacter aurescens
J. Biochem.
78
1183-1190
1975
Paenarthrobacter aurescens
Kitamikado, M.; Lee, Y.Z.
Chondroitinase-producing bacteria in natural habitats
Appl. Microbiol.
29
414-421
1975
Aeromonas sp.
Gu, K.; Linhardt, R.L.; Laliberte, M.; Gu, K.; Zimmermann, J.
Purification, characterization and specificity of chondroitin lyases and glycuronidase from Flavobacterium heparinum
Biochem. J.
312
569-577
1995
Pedobacter heparinus
Fethiere, J.; Eggimann, B.; Cygler, M.
Crystal structure of chondroitin AC lyase, a representative of a family of glycosaminoglycan degrading enzymes
J. Mol. Biol.
288
635-647
1999
Pedobacter heparinus
Griffin, B.R.
Characteristics of a chondroitin AC lyase produced by Cytophaga columnaris
Trans. Am. Fish. Soc.
120
391-395
1991
Flavobacterium columnare
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Fethiere, J.; Shilton, B.H.; Li, Y.; Allaire, M.; Laliberte, M.; Eggimann, B.; Cygler, M.
Crystallization and preliminary analysis of chondroitinase AC from Flavobacterium heparinum
Acta Crystallogr. Sect. D
54
279-280
1998
Pedobacter heparinus
Rye, C.S.; Withers, S.G.
Development of an assay and determination of kinetic parameters for chondroitin AC lyase using defined synthetic substrates
Anal. Biochem.
308
77-82
2002
Pedobacter heparinus
Tkalec, A.L.; Fink, D.; Blain, F.; Zhang-Sun, G.; Laliberte, M.; Bennett, D.C.; Gu, K.; Zimmermann, J.J.F.; Su, H.
Isolation and expression in Escherichia coli of cslA and cslB, genes coding for the chondroitin sulfate-degrading enzymes chondroitinase AC and chondroitinase B, respectively, from Flavobacterium heparinum
Appl. Environ. Microbiol.
66
29-35
2000
Pedobacter heparinus (Q59288), Pedobacter heparinus
Pojasek, K.; Shriver, Z.; Kiley, P.; Venkataraman, G.; Sasisekharan, R.
Recombinant expression, purification, and kinetic characterization of chondroitinase AC and chondroitinase B from Flavobacterium heparinum
Biochem. Biophys. Res. Commun.
286
343-351
2001
Pedobacter heparinus
Huang, W.; Boju, L.; Tkalec, L.; Su, H.; Yang, H.O.; Gunay, N.S.; Linhardt, R.J.; Kim, Y.S.; Matte, A.; Cygler, M.
Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis
Biochemistry
40
2359-2372
2001
Pedobacter heparinus (Q59288)
Capila, I.; Wu, Y.; Rethwisch, D.W.; Matte, A.; Cygler, M.; Linhardt, R.J.
Role of arginine 292 in the catalytic activity of chondroitin AC lyase from Flavobacterium heparinum
Biochim. Biophys. Acta
1597
260-270
2002
Pedobacter heparinus
Hong, S.W.; Kim, B.T.; Shin, H.Y.; Kim, W.S.; Lee, K.S.; Kim, Y.S.; Kim, D.H.
Purification and characterization of novel chondroitin ABC and AC lyases from Bacteroides stercoris HJ-15, a human intestinal anaerobic bacterium
Eur. J. Biochem.
269
2934-2940
2002
Bacteroides stercoris, Bacteroides stercoris HJ-15
Rye, C.S.; Withers, S.G.
Elucidation of the mechanism of polysaccharide cleavage by chondroitin AC lyase from Flavobacterium heparinum
J. Am. Chem. Soc.
124
9756-9767
2002
Pedobacter heparinus
Suzuki, K.; Terasaki, Y.; Uyeda, M.
Inhibition of hyaluronidases and chondroitinases by fatty acids
J. Enzyme Inhib. Med. Chem.
17
183-186
2002
Paenarthrobacter aurescens, Pedobacter heparinus
Lunin, V.V.; Li, Y.; Linhardt, R.J.; Miyazono, H.; Kyogashima, M.; Kaneko, T.; Bell, A.W.; Cygler, M.
High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism
J. Mol. Biol.
337
367-386
2004
Paenarthrobacter aurescens
Xie, H.X.; Nie, P.; Chang, M.X.; Liu, Y.; Yao, W.J.
Gene cloning and functional analysis of glycosaminoglycan-degrading enzyme chondroitin AC lyase from Flavobacterium columnare G4
Arch. Microbiol.
184
49-55
2005
Flavobacterium columnare, Flavobacterium columnare G4
Ke, T.; Zhangfu, L.; Qing, G.; Yong, T.; Hong, J.; Hongyan, R.; Kun, L.; Shigui, L.
Isolation of Serratia marcescens as a chondroitinase-producing bacterium and purification of a novel chondroitinase AC
Biotechnol. Lett.
27
489-493
2005
Serratia marcescens
Rye, C.S.; Withers, S.G.
The synthesis of a novel thio-linked disaccharide of chondroitin as a potential inhibitor of polysaccharide lyases
Carbohydr. Res.
339
699-703
2004
Pedobacter heparinus
Hirano, K.; Sakai, S.; Ishikawa, T.; Avci, F.Y.; Linhardt, R.J.; Toida, T.
Preparation of the methyl ester of hyaluronan and its enzymatic degradation
Carbohydr. Res.
340
2297-2304
2005
Paenarthrobacter aurescens
Rye, C.S.; Matte, A.; Cygler, M.; Withers, S.G.
An atypical approach identifies TYR234 as the key base catalyst in chondroitin AC lyase
ChemBioChem
7
631-637
2006
Pedobacter heparinus
Makovitzky, J.; Richter, S.; Appel, T.R.
Topooptical investigations and enzymatic digestions on tissue-isolated amyloid fibrils
Acta Histochem.
108
193-196
2006
Pedobacter heparinus
Suomalainen, L.R.; Tiirola, M.; Valtonen, E.T.
Chondroitin AC lyase activity is related to virulence of fish pathogenic Flavobacterium columnare
J. Fish Dis.
29
757-763
2006
Flavobacterium columnare
Zhang, Z.; Park, Y.; Kemp, M.M.; Zhao, W.; Im, A.R.; Shaya, D.; Cygler, M.; Kim, Y.S.; Linhardt, R.J.
Liquid chromatography-mass spectrometry to study chondroitin lyase action pattern
Anal. Biochem.
385
57-64
2009
Paenarthrobacter aurescens, Pedobacter heparinus
Volpi, N.; Maccari, F.
Structural characterization and antithrombin activity of dermatan sulfate purified from marine clam Scapharca inaequivalvis
Glycobiology
19
356-367
2008
Paenarthrobacter aurescens, Pedobacter heparinus
Coulson-Thomas, Y.M.; Coulson-Thomas, V.J.; Filippo, T.R.; Mortara, R.A.; da Silveira, R.B.; Nader, H.B.; Porcionatto, M.A.
Adult bone marrow-derived mononuclear cells expressing chondroitinase AC transplanted into CNS injury sites promote local brain chondroitin sulphate degradation
J. Neurosci. Methods
171
19-29
2008
Pedobacter heparinus (Q59288), Pedobacter heparinus
Shim, K.W.; Kim, D.H.
Cloning and expression of chondroitinase AC from Bacteroides stercoris HJ-15
Protein Expr. Purif.
58
222-228
2008
Bacteroides stercoris (A9Y5J0)
Flangea, C.; Schiopu, C.; Sisu, E.; Serb, A.; Przybylski, M.; Seidler, D.G.; Zamfir, A.D.
Determination of sulfation pattern in brain glycosaminoglycans by chip-based electrospray ionization ion trap mass spectrometry
Anal. Bioanal. Chem.
395
2489-2498
2009
Pedobacter heparinus
Zamfir, A.D.; Flangea, C.; Sisu, E.; Serb, A.F.; Dinca, N.; Bruckner, P.; Seidler, D.G.
Analysis of novel over- and under-sulfated glycosaminoglycan sequences by enzyme cleavage and multiple stage MS
Proteomics
9
3435-3444
2009
Pedobacter heparinus
Zamfir, A.D.; Flangea, C.; Sisu, E.; Seidler, D.G.; Peter-Katalinic J.
Combining size-exclusion chromatography and fully automated chip-based nanoelectrospray quadrupole time-of-flight tandem mass spectrometry for structural analysis of chondroitin/dermatan sulfate in human decorin
Electrophoresis
32
1639-1646
2011
Homo sapiens
Kunttu, H.M.; Jokinen, E.I.; Valtonen, E.T.; Sundberg, L.R.
Virulent and nonvirulent Flavobacterium columnare colony morphologies: characterization of chondroitin AC lyase activity and adhesion to polystyrene
J. Appl. Microbiol.
111
1319-1326
2011
Flavobacterium columnare
Williams, A.; He, W.; Cress, B.F.; Liu, X.; Alexandria, J.; Yoshizawa, H.; Nishimura, K.; Toida, T.; Koffas, M.; Linhardt, R.J.
Cloning and expression of recombinant chondroitinase ACII and its comparison to the Arthrobacter aurescens enzyme
Biotechnol. J.
12
1700239
2017
Paenarthrobacter aurescens, Paenarthrobacter aurescens 161MFSha2.1
Tao, L.; Song, F.; Xu, N.; Li, D.; Linhardt, R.J.; Zhang, Z.
New insights into the action of bacterial chondroitinase AC I and hyaluronidase on hyaluronic acid
Carbohydr. Polym.
158
85-92
2017
Pedobacter heparinus
Rani, A.; Dhillon, A.; Sharma, K.; Goyal, A.
Insights into the structural characteristics and substrate binding analysis of chondroitin AC lyase (PsPL8A) from Pedobacter saltans
Int. J. Biol. Macromol.
109
980-991
2018
Pseudopedobacter saltans (F0S764), Pseudopedobacter saltans, Pseudopedobacter saltans DSM 12145 (F0S764)
Rani, A.; Goyal, A.
A new member of family 8 polysaccharide lyase chondroitin AC lyase (PsPL8A) from Pedobacter saltans displays endo- and exo-lytic catalysis
J. Mol. Catal. B
134
215-224
2016
Pseudopedobacter saltans (F0S764), Pseudopedobacter saltans DSM 12145 (F0S764)
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