Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
formaldehyde + glutathione + NAD+ | Homo sapiens | the enzyme activity in increased in livers from cancer patients independent of alcohol drinking or nondrinking, with no significant differences between primary and metastatic tumors | S-formylglutathione + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | from healthy individuals, cancer patients, including drinkers and nondrinkers | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
enzyme activities in livers from healthy individuals, cancer patients, including drinkers and nondrinkers, overview | Homo sapiens |
0.00089 | - |
activity in livers from healthy persons, drinkers and nondrinkers | Homo sapiens |
0.0012 | - |
activity in livers from cancer patients, drinkers and nondrinkers | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formaldehyde + glutathione + NAD+ | the enzyme activity in increased in livers from cancer patients independent of alcohol drinking or nondrinking, with no significant differences between primary and metastatic tumors | Homo sapiens | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | the true substrate is S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Homo sapiens | S-formylglutathione + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADH III | - |
Homo sapiens |
class III ADH | - |
Homo sapiens |
class III alcohol dehydrogenase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |