Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | key enzyme of the bile acid biosynthetic pathway. It regulates the composition of bile acids in bile, i.e. ratio between cholic acid and chenodeoxycholic acid. Bile acids inhibit CYP8B1 gene transcription by inducing alpha-fetoprotein transcription factor and inhibiting HNF4alpha expression | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | key enzyme of the bile acid biosynthetic pathway. It regulates the composition of bile acids in bile, i.e. ratio between cholic acid and chenodeoxycholic acid. Bile acids inhibit CYP8B1 gene transcription by inducing alpha-fetoprotein transcription factor and inhibiting HNF4alpha expression | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
12alpha-hydroxylase gene | - |
Rattus norvegicus |
CYP8B1 | - |
Rattus norvegicus |