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Literature summary for 1.2.1.105 extracted from

  • Condori-Apfata, J.A.; Batista-Silva, W.; Medeiros, D.B.; Vargas, J.R.; Valente, L.M.L.; Heyneke, E.; Perez-Diaz, J.L.; Fernie, A.R.; Araujo, W.L.; Nunes-Nesi, A.
    The Arabidopsis E1 subunit of the 2-oxoglutarate dehydrogenase complex modulates plant growth and seed production (2019), Plant Mol. Biol., 101, 183-202 .
    View publication on PubMed
Search for more literature for 1.2.1.105

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
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 Arabidopsis thaliana 5739
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana F4IWV2 component E1, 2-oxoglutarate dehydrogenase isoform 1, cf. EC 1.2.4.2
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Arabidopsis thaliana Q9FLH2 component E1, 2-oxoglutarate dehydrogenase isoform 2, cf. EC 1.2.4.2
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Arabidopsis thaliana Q9FLH2 isoform 2-OGDH2, cf. EC 1.2.4.2
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Source Tissue

Source Tissue Comment Organism Textmining
epidermis guard cell-enriched epidermal fragments, higher expression levels of isoform 2-OGDH1 than isoform 2-OGDH2 Arabidopsis thaliana
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flower isoform E1-OGDH2 is slightly more expressed in cauline leaf and flowers Arabidopsis thaliana
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leaf young, mature, senescent leaves, lesaf blade and midrib, show higher expression levels of isoform 2-OGDH1 than isoform 2-OGDH2. Isoform E1-OGDH2 is slightly more expressed in cauline leaf and flowers Arabidopsis thaliana
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root higher expression levels of isoform 2-OGDH1 than isoform 2-OGDH2 Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
2-OGDH2
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 Arabidopsis thaliana
At3g55410
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 Arabidopsis thaliana
At5g65750
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 Arabidopsis thaliana
MPA24.10 gene name, cf. EC 1.2.4.2 Arabidopsis thaliana
ODGH1
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 Arabidopsis thaliana
ODGH2
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function mutant plants lacking component E1 isoform OGDH1 or OGDH2 exhibit substantial reduction in both respiration and CO2 assimilation rates. Mutant lines exhibit reduced levels of chlorophylls and nitrate, increased levels of sucrose, malate and fumarate and minor changes in total protein and starch levels in leaves. After 4 weeks of growth, a clear decrease in the shoot growth of the OGDH1 mutant lines is observed, while OGDH2 mutant lines exhibit increased growth in comparison to wild type plants. The leaf number is unaltered in OGDH1 mutant lines and increased in OGDH2 mutant lines. Repression of the OGDH1 gene leads to a significative reduction of silique length and the number of seeds per silique. Lack of expression of the OEGDH2 gene does not affect the silique length, but decreases the number of seeds per silique. Isoform OGDH1 is essential to the final 2-OGDH activity in leaves while isoform OGDH2 is not Arabidopsis thaliana
physiological function two genes encode for the E1 subunit of 2-OGDH. Insertion knockout mutant lines for each of the genes exhibit substantial reduction in both respiration and CO2 assimilation rates. Mutant lines exhibit reduced levels of chlorophylls and nitrate, increased levels of sucrose, malate and fumarate and minor changes in total protein and starch levels in leaves. Absence in expression of E1-OGDH2 gene does not affect the silique length, but decreased the number of seeds per silique. In seedlings lacking only the expression of E1-OGDH2 the root growth is invariant from that of wild type seedlings Arabidopsis thaliana