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Literature summary for 1.4.3.22 extracted from

  • Kettner, L.; Braun, C.; Seitl, I.; Pross, E.; Fischer, L.
    Production and characterization of a new diamine oxidase from Yarrowia lipolytica (2021), J. Biotechnol., 340, 39-46 .
    View publication on PubMed
Search for more literature for 1.4.3.22

Application

Application Comment Organism
food industry degradation of biogenic amines Yarrowia lipolytica

Cloned(Commentary)

Cloned (Comment) Organism
homologously recombinantly integrated into the genome of Yarrowia lipolytica PO1f using the CRISPR-Cas9 system for the subsequent production of diamine oxidase in a bioreactor Yarrowia lipolytica

Inhibitors

Inhibitors Comment Organism Structure
histamine substrate inhibition at concentrations greater than 12.5 mM Yarrowia lipolytica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3
-
 histamine pH 7.2, 37°C Yarrowia lipolytica

Organism

Organism UniProt Comment Textmining
Yarrowia lipolytica
-
-
-
Yarrowia lipolytica PO1f
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Yarrowia lipolytica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
agmatine + H2O + O2
-
 Yarrowia lipolytica ?
-
 ?
agmatine + H2O + O2
-
 Yarrowia lipolytica PO1f ?
-
 ?
cadaverine + H2O + O2
-
 Yarrowia lipolytica 5-aminopentanal + NH3 + H2O2
-
 ?
cadaverine + H2O + O2
-
 Yarrowia lipolytica PO1f 5-aminopentanal + NH3 + H2O2
-
 ?
histamine + O2 + H2O degrades around 75% of the histamine used in a bioconversion experiment with a food-relevant concentration of 150 mg/l Yarrowia lipolytica (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
histamine + O2 + H2O degrades around 75% of the histamine used in a bioconversion experiment with a food-relevant concentration of 150 mg/l Yarrowia lipolytica PO1f (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
putrescine + H2O + O2
-
 Yarrowia lipolytica 4-aminobutanal + NH3 + H2O2
-
 ?
tryptamine + H2O + O2
-
 Yarrowia lipolytica 1H-indol-3-ylacetaldehyde + NH3 + H2O2
-
 ?
tryptamine + H2O + O2
-
 Yarrowia lipolytica PO1f 1H-indol-3-ylacetaldehyde + NH3 + H2O2
-
 ?
tyramine + H2O + O2
-
 Yarrowia lipolytica 4-hydroxyphenylethanal + NH3 + H2O2
-
 ?
tyramine + H2O + O2
-
 Yarrowia lipolytica PO1f 4-hydroxyphenylethanal + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
DAO-1
-
 Yarrowia lipolytica

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40
-
-
 Yarrowia lipolytica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
 in Tris-HCl buffer (50 mM) with histamine as substrate Yarrowia lipolytica

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
61.89
-
 histamine pH 7.2, 37°C Yarrowia lipolytica