BRENDA - Enzyme Database show
show all sequences of 1.5.99.B2

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

Hu, C.A.; Donald, S.P.; Yu, J.; Lin, W.W.; Liu, Z.; Steel, G.; Obie, C.; Valle, D.; Phang, J.M.; Mol. Cell. Biochem. 295, 85-92 (2007)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
L-proline
in the presence of L-proline, high POX activity is sufficient to induce mitochondria-mediated apoptosis
Homo sapiens
Cloned(Commentary)
Commentary
Organism
expressed in DLD-1.POX cells
Homo sapiens
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Homo sapiens
5739
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
colorectal cancer cell
-
Homo sapiens
-
DLD-1 cell
-
Homo sapiens
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-proline + cytochrome c + H2O
-
675953
Homo sapiens
(S)-1-pyrroline-5-carboxylate + reduced cytochrome c
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
FAD
-
Homo sapiens
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
L-proline
in the presence of L-proline, high POX activity is sufficient to induce mitochondria-mediated apoptosis
Homo sapiens
Cloned(Commentary) (protein specific)
Commentary
Organism
expressed in DLD-1.POX cells
Homo sapiens
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
FAD
-
Homo sapiens
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Homo sapiens
5739
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
colorectal cancer cell
-
Homo sapiens
-
DLD-1 cell
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-proline + cytochrome c + H2O
-
675953
Homo sapiens
(S)-1-pyrroline-5-carboxylate + reduced cytochrome c
-
-
-
?
Other publictions for EC 1.5.99.B2
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743113
Huijbers
-
A more polar N-terminal helix ...
Thermus thermophilus
J. Mol. Catal. B
134
340-346
2016
-
-
1
1
1
-
1
7
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
2
1
1
-
6
1
-
-
1
4
-
-
-
-
1
1
1
1
-
-
1
4
7
-
-
-
1
-
-
-
-
-
-
-
-
2
2
1
1
-
6
1
-
-
-
-
-
-
-
6
6
742204
Monteoliva
Context of action of proline ...
Arabidopsis thaliana
BMC Plant Biol.
14
21
2014
-
-
1
-
1
-
-
-
1
-
-
1
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
1
1
1
1
-
-
724080
Kawakami
Comparative analysis of the ca ...
Pyrococcus furiosus, Pyrococcus horikoshii, Pyrococcus horikoshii OT-3, Thermococcus kodakarensis, Thermococcus kodakarensis KOD1 JCM 12380, Thermococcus profundus, Thermococcus profundus DSM 9503
Appl. Microbiol. Biotechnol.
97
3419-3427
2013
-
-
4
-
-
-
4
8
-
-
-
-
-
51
-
-
4
-
-
-
-
-
28
4
8
-
4
8
-
-
-
4
8
-
-
-
-
4
4
-
-
-
-
4
8
8
-
-
-
-
-
-
-
4
-
-
-
-
28
4
8
-
4
8
-
-
-
-
-
-
-
-
-
-
725126
Omidinia
Expression, purification and c ...
Pseudomonas putida, Pseudomonas putida POS-F84
Indian J. Microbiol.
53
297-302
2013
-
-
1
-
-
-
-
1
-
-
1
-
-
2
-
-
1
-
-
-
-
-
8
1
1
-
1
-
1
1
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
1
-
-
1
-
-
-
-
1
-
-
-
-
8
1
1
-
1
-
1
1
-
-
-
-
-
-
-
-
725607
Mohammadi
Process integration for the re ...
Pseudomonas fluorescens
J. Chromatogr. B
929
11-17
2013
-
-
1
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
1
-
-
-
1
1
-
-
-
-
-
-
-
1
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
741885
Serrano
Kinetic and isotopic characte ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Biochemistry
52
5009-5015
2013
-
-
1
-
2
-
-
4
-
-
-
2
-
2
-
-
1
1
-
-
-
-
4
-
1
-
-
2
1
-
-
1
-
-
-
-
-
1
1
-
2
-
-
-
-
4
-
-
-
2
-
-
-
1
-
-
-
-
4
-
1
-
-
2
1
-
-
-
-
3
3
-
2
2
742973
Mohammadi
Process integration for the r ...
Pseudomonas fluorescens
J. Chromatogr. B
929
11-17
2013
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
1
-
1
-
1
-
-
-
1
-
-
1
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
1
-
1
-
1
-
-
-
1
-
-
1
-
1
1
-
-
-
723984
Mohammadi
Proline dehydrogenase from Pse ...
Pseudomonas fluorescens, Pseudomonas fluorescens Pf-5
Appl. Biochem. Microbiol.
48
167-174
2012
-
-
1
-
-
-
-
1
-
-
1
-
-
5
-
-
-
-
-
-
-
-
17
1
1
1
-
-
1
1
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
17
1
1
1
-
-
1
1
-
-
-
-
-
-
-
-
724329
Luo
Crystal structures and kinetic ...
Deinococcus radiodurans
Biochemistry
51
10099-10108
2012
-
-
1
1
2
-
-
6
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
6
-
-
-
1
-
-
-
-
-
1
1
1
2
-
-
-
-
6
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
725476
Sakuraba
Crystal structure of novel dye ...
Aeropyrum pernix
J. Biol. Chem.
287
20070-20080
2012
-
-
1
1
-
-
-
2
-
-
2
-
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
2
-
-
2
-
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
726429
Tallarita
Expression in Escherichia coli ...
Homo sapiens
Protein Expr. Purif.
82
345-351
2012
-
-
1
-
-
-
2
1
1
-
3
-
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
2
-
1
1
-
3
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
727195
Satomura
Gene expression and characteri ...
Aeropyrum pernix
Biosci. Biotechnol. Biochem.
76
589-593
2012
-
-
1
-
-
-
-
2
-
3
2
-
-
1
-
-
1
-
-
-
1
-
3
1
2
-
2
-
1
-
1
1
-
-
-
-
-
1
1
-
-
-
-
-
-
2
-
3
2
-
-
-
-
1
-
-
1
-
3
1
2
-
2
-
1
-
1
-
-
-
-
-
-
-
724048
Satomura
Characterization of a novel dy ...
Pyrobaculum calidifontis, Pyrobaculum calidifontis JCM 11548
Appl. Microbiol. Biotechnol.
89
1075-1082
2011
-
-
1
-
-
-
-
4
-
-
3
-
-
3
-
-
1
-
-
-
2
-
10
1
1
-
1
-
1
1
1
1
-
-
-
-
-
1
1
-
-
-
-
-
-
4
-
-
3
-
-
-
-
1
-
-
2
-
10
1
1
-
1
-
1
1
1
-
-
-
-
-
-
-
726218
Cecchini
Proline dehydrogenase contribu ...
Arabidopsis thaliana
Plant Physiol.
155
1947-1959
2011
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
710742
Satomura
Crystallization and preliminar ...
Aeropyrum pernix
Acta Crystallogr. Sect. F
66
1508-1510
2010
-
-
1
1
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
711615
Funck
Non-redundant functions of two ...
Arabidopsis thaliana
BMC Plant Biol.
10
70
2010
-
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684911
Maxwell
Identification of a p53-respon ...
Homo sapiens
Biochem. Biophys. Res. Commun.
369
308-313
2008
-
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
685248
White
Structural basis for the inact ...
Thermus thermophilus
Biochemistry
47
5573-5580
2008
-
-
1
1
-
-
1
-
1
-
1
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
-
1
1
1
-
-
-
1
1
-
1
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689987
Di Rosa
Type I hyperprolinemia and pro ...
Homo sapiens
Psychiatr. Genet.
18
40-42
2008
-
1
-
-
15
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
15
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695364
Schuermann
Three crystal forms of the bif ...
Bradyrhizobium japonicum
Acta Crystallogr. Sect. F
64
949-953
2008
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695521
Phang
The metabolism of proline, a s ...
Homo sapiens
Amino Acids
35
681-690
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
699706
Mitsubuchi
Inborn errors of proline metab ...
Homo sapiens
J. Nutr.
138
2016S-2020S
2008
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
3
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
3
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675953
Hu
Overexpression of proline oxid ...
Homo sapiens
Mol. Cell. Biochem.
295
85-92
2007
1
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
686651
Monaghan
Mechanistic aspects and redox ...
Pyrococcus furiosus
FEBS J.
274
2070-2087
2007
-
-
1
-
3
-
-
9
1
-
2
-
-
1
-
-
1
-
-
-
-
-
4
1
-
-
1
9
-
1
1
3
-
-
-
-
-
1
3
-
3
-
-
-
-
9
1
-
2
-
-
-
-
1
-
-
-
-
4
1
-
-
1
9
-
1
1
-
-
-
-
-
-
-
687234
Huang
DELTA1-pyrroline-5-carboxylic ...
Bacillus subtilis
J. Agric. Food Chem.
55
5097-5102
2007
-
-
1
-
-
-
-
-
1
-
2
-
-
1
-
-
1
-
-
-
1
-
1
-
1
-
1
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
2
-
-
-
-
1
-
-
1
-
1
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
687550
White
Structure and kinetics of mono ...
Thermus thermophilus
J. Biol. Chem.
282
14316-14327
2007
-
-
1
1
-
-
4
3
1
-
1
-
-
1
-
-
1
-
-
-
-
-
5
-
-
-
1
3
-
-
-
1
3
-
-
-
-
1
1
1
-
-
-
4
3
3
1
-
1
-
-
-
-
1
-
-
-
-
5
-
-
-
1
3
-
-
-
-
-
-
-
-
-
-
689071
Kim
Apoptotic action of peroxisome ...
Homo sapiens
Mol. Pharmacol.
72
674-685
2007
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689670
Ribarits
Two tobacco proline dehydrogen ...
Nicotiana tabacum
Planta
225
1313-1324
2007
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
8
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
16
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690036
Kolodyazhnaya
-
Tobacco transformants expressi ...
Nicotiana tabacum
Russ. J. Genet.
43
825-828
2007
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
677108
Kolodyazhnaya
-
Evaluation of salt tolerance i ...
Nicotiana tabacum
Russ. J. Genet.
42
212-214
2006
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
660326
Miller
Responsive modes of Medicago s ...
Medicago sativa
Planta
222
70-79
2005
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671083
White
Cloning, purification and crys ...
Thermus thermophilus
Acta Crystallogr. Sect. F
61
737-739
2005
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671084
Monaghan
Crystallization and preliminar ...
Pyrococcus furiosus
Acta Crystallogr. Sect. F
61
756-758
2005
-
-
1
1
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
673527
Kawakami
A second novel dye-linked L-pr ...
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
FEBS J.
272
4044-4054
2005
-
-
-
-
-
-
-
2
-
-
8
-
-
45
-
-
-
-
-
-
2
-
4
2
-
-
1
-
1
-
1
3
-
-
-
-
-
-
3
-
-
-
-
-
-
2
-
-
8
-
-
-
-
-
-
-
2
-
4
2
-
-
1
-
1
-
1
-
-
-
-
-
-
-
674471
Tsuge
Crystal structure of a novel F ...
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
J. Biol. Chem.
280
31045-31049
2005
-
-
-
1
-
-
-
-
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
3
-
-
-
-
-
-
4
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
659027
Lee
Characterization of the Vibrio ...
Vibrio vulnificus
J. Bacteriol.
185
3842-3852
2003
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
660194
Abraham
Light-dependent induction of p ...
Arabidopsis sp.
Plant Mol. Biol.
51
363-372
2003
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
392566
Mani
Altered levels of proline dehy ...
Arabidopsis thaliana
Plant Physiol.
128
73-83
2002
-
-
-
-
1
-
-
-
1
-
1
-
-
3
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
392568
Tritsch
Mechanism-based inhibition of ...
Drosophila melanogaster, Glossina morsitans, Rattus norvegicus
Biochim. Biophys. Acta
1202
77-81
1993
-
-
-
-
-
-
5
1
1
-
-
-
-
3
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
5
1
1
1
-
-
-
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
392557
Meile
Purification and properties of ...
Pseudomonas aeruginosa, Salmonella enterica subsp. enterica serovar Typhimurium
Eur. J. Biochem.
129
67-75
1982
-
-
-
-
-
-
4
1
-
-
2
2
-
2
-
-
1
1
-
-
2
1
5
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
4
-
1
-
-
2
2
-
-
-
1
-
-
2
1
5
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
392558
Elthon
Proline oxidation in corn mito ...
Zea mays
Plant Physiol.
70
567-572
1982
-
-
-
-
-
-
-
-
2
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
392559
Mommsen
Respiratory and enzymatic prop ...
Illex illecebrosus
Eur. J. Biochem.
120
345-350
1981
-
-
-
-
-
-
-
-
2
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
392561
Balboni
Studies on the inner mitochond ...
Phormia regina
Biochim. Biophys. Acta
462
171-176
1977
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
392562
Kramar
Solubilization of proline dehy ...
Rattus norvegicus
Hoppe-Seyler's Z. Physiol. Chem.
352
1267-1270
1971
-
-
-
-
-
-
-
2
2
-
-
1
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
2
-
-
1
-
-
-
1
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
392563
Crabtree
The activities of proline dehy ...
insecta
Biochem. J.
117
1019-1021
1970
-
-
-
-
-
-
-
1
2
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
2
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
392564
Hansford
The control of the oxidation o ...
Phormia regina
J. Biol. Chem.
245
991-994
1970
1
-
-
-
-
-
-
2
1
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-