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Literature summary for 7.1.1.2 extracted from
- Isolation of the iron-sulfur-containing polypeptides of NADH: oxidoreductase ubiquinone (1986), Methods Enzymol., 126, 360-369.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Bos taurus | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Iron | enzyme contains Fe-S clusters | Bos taurus |  |
| Iron | the NADH:ubiquinone oxidoreductase complex is composed of three distinct fragments: 1. IP: a water soluble Fe-S-protein that is composed of 5-6 polypeptides and contains four Fe-S clusters, 2. FP: a water-soluble Fe-S-flavoprotein that is composed of three polypeptides and contains FMN and two Fe-S clusters, 3. a water-insoluble fraction containing phospholipids and hydrophobic polypeptides | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| lipoprotein | the NADH:ubiquinone oxidoreductase complex is composed of three distinct fragments: 1. IP: a water soluble Fe-S-protein that is composed of 5-6 polypeptides and contains four Fe-S clusters, 2. FP: a water-soluble FeS-flavoprotein that is composed of three polypeptides and contains FMN and two FeS clusters, 3. a water-insoluble fraction containing phospholipids and hydrophobic polypeptides | Bos taurus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + ubiquinone | - |
Bos taurus | NAD+ + ubiquinol | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | the NADH:ubiquinone oxidoreductase complex is composed of three distinct fragments: 1. IP: a water soluble Fe-S-protein that is composed of 5-6 polypeptides and contains four Fe-S clusters, 2. FP: a water-soluble FeS-flavoprotein that is composed of three polypeptides and contains FMN and two FeS clusters, 3. a water-insoluble fraction containing phospholipids and hydrophobic polypeptides | Bos taurus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FMN | enzyme contains FMN | Bos taurus | |
| NADH | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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