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Literature summary for 7.1.1.2 extracted from
- Comparison of the inhibitory action of synthetic capsaicin analogs with various NADH-ubiquinone oxidoreductases (1996), Biochim. Biophys. Acta, 1273, 21-30.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-(4-benzyl-phenoxy)-N-(3,4-dimethoxy-benzyl)-benzamide | - |
Escherichia coli |  |
| 4-(4-tert-butyl-phenoxy)-N-(3,4-dimethoxy-benzyl)-benzamide | - |
Bos taurus | |
| 4-(4-tert-butyl-phenoxy)-N-(3,4-dimethoxy-benzyl)-benzamide | - |
Solanum tuberosum | |
| capsaicin | and synthetic capsaicin analogue. Several synthetic capsaicins discriminate between NDH-1 and NDH-2 much better than natural capsaicin | Bos taurus | |
| capsaicin | and synthetic capsaicin analogue. Several synthetic capsaicins discriminate between NDH-1 and NDH-2 much better than natural capsaicin | Escherichia coli | |
| capsaicin | and synthetic capsaicin analogue. Several synthetic capsaicins discriminate between NDH-1 and NDH-2 much better than natural capsaicin | Solanum tuberosum | |
| N-(3,4-dimethoxy-benzyl)-4-[4-(1,1-dimethyl-propyl)-phenoxy]-benzamide | - |
Escherichia coli | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Bos taurus | 5739 | - |
| mitochondrion | - |
Solanum tuberosum | 5739 | - |
| plasma membrane | - |
Escherichia coli | 5886 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + ubiquinone | Escherichia coli | - |
? | - |
? | |
| NADH + ubiquinone | Bos taurus | proton-translocating enzyme | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
NDH-1 | - |
| Escherichia coli | - |
NDH-1 and NDH-2 | - |
| Solanum tuberosum | - |
NDH-1 and NDH-2 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Bos taurus | - |
| tuber | - |
Solanum tuberosum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + ubiquinone | - |
Escherichia coli | NAD+ + ubiquinol | - |
? | |
| NADH + ubiquinone | - |
Solanum tuberosum | NAD+ + ubiquinol | - |
? | |
| NADH + ubiquinone | proton-translocating enzyme | Bos taurus | NAD+ + ubiquinol | - |
? | |
| NADH + ubiquinone | - |
Escherichia coli | ? | - |
? | |
| NADH + ubiquinone | proton-translocating enzyme | Bos taurus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NDH-1 | proton-pumping NADH-ubiquinone oxidoreductase | Bos taurus |
| NDH-2 | non-proton-pumping NADH-ubiquinone oxidoreductase | Escherichia coli |
| NDH-2 | non-proton-pumping NADH-ubiquinone oxidoreductase | Solanum tuberosum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Escherichia coli | |
| NADH | - |
Bos taurus | |
| NADH | - |
Solanum tuberosum | |
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