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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for protein targeting to ER
Gene ontology ID
GO:0045047
Definition
The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane
Synonyms
1. protein targeting to endoplasmic reticulum
2. protein-endoplasmic reticulum targeting
3. protein-ER targeting
References
1. ISBN 0716731363
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