EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.1.358 | 2-dehydropantolactone + NADPH + H+ |
- |
Candida dubliniensis |
(R)-pantolactone + NADP+ |
- |
? |
1.1.1.358 | more |
enzyme CduCPR shows high catalytic activity and stereoselectivity using 2-dehydropantolactone (KPL) as the substrate. In a continuous feeding reaction, 200 mM ketopantolactone is reduced to (R)-pantolactone with 98% conversion and 99% enantiomeric excess within 2.0 h by the purified recombinant enzyme |
Candida dubliniensis |
? |
- |
- |
1.1.1.358 | more |
product identification and quantification by gas chromatography. Optimization of the reaction conditions for the synthesis of (R)-(-)-pantolactone |
Candida dubliniensis |
? |
- |
- |
1.1.1.358 | 2-dehydropantolactone + NADPH + H+ |
- |
Candida dubliniensis ATCC MYA-646 |
(R)-pantolactone + NADP+ |
- |
? |
1.1.1.358 | more |
enzyme CduCPR shows high catalytic activity and stereoselectivity using 2-dehydropantolactone (KPL) as the substrate. In a continuous feeding reaction, 200 mM ketopantolactone is reduced to (R)-pantolactone with 98% conversion and 99% enantiomeric excess within 2.0 h by the purified recombinant enzyme |
Candida dubliniensis ATCC MYA-646 |
? |
- |
- |
1.1.1.358 | more |
product identification and quantification by gas chromatography. Optimization of the reaction conditions for the synthesis of (R)-(-)-pantolactone |
Candida dubliniensis ATCC MYA-646 |
? |
- |
- |
1.1.1.358 | 2-dehydropantolactone + NADPH + H+ |
- |
Candida dubliniensis CBS 7987 |
(R)-pantolactone + NADP+ |
- |
? |
1.1.1.358 | more |
enzyme CduCPR shows high catalytic activity and stereoselectivity using 2-dehydropantolactone (KPL) as the substrate. In a continuous feeding reaction, 200 mM ketopantolactone is reduced to (R)-pantolactone with 98% conversion and 99% enantiomeric excess within 2.0 h by the purified recombinant enzyme |
Candida dubliniensis CBS 7987 |
? |
- |
- |
1.1.1.358 | more |
product identification and quantification by gas chromatography. Optimization of the reaction conditions for the synthesis of (R)-(-)-pantolactone |
Candida dubliniensis CBS 7987 |
? |
- |
- |
1.1.1.358 | 2-dehydropantolactone + NADPH + H+ |
- |
Candida dubliniensis CD36 |
(R)-pantolactone + NADP+ |
- |
? |