EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.7.4.25 | Alzheimer Disease |
21681968 |
First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors. |
unassigned |
0 |
| 2.7.4.25 | Brain Ischemia |
21517148 |
ROCK inhibition prevents tau hyperphosphorylation and p25/CDK5 increase after global cerebral ischemia. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 2.7.4.25 | Infections |
31872217 |
Involvement of the chloroplast gene ferredoxin 1 in multiple responses of N. benthamiana to Potato virus X infection. |
therapeutic application
unassigned |
1
0 |
| 2.7.4.25 | Malaria |
22037467 |
Structure of Fab fragment of malaria transmission blocking antibody 2A8 against P. vivax P25 protein. |
therapeutic application
unassigned |
2
0 |
| 2.7.4.25 | Myasthenia Gravis |
14990122 |
[Expression and tissue and species specificity of P25 protein in patients with myasthenia gravis] |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
1
2
0 |
| 2.7.4.25 | Neoplasms |
179702 |
Differences between pyrimidine nucleoside monophosphate kinase from rat Novikoff ascites hepatoma and rat liver. |
ongoing research
unassigned |
3
0 |
| 2.7.4.25 | Neurodegenerative Diseases |
22049418 |
Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of ?-secretase (BACE1). |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 2.7.4.25 | Tauopathies |
21517148 |
ROCK inhibition prevents tau hyperphosphorylation and p25/CDK5 increase after global cerebral ischemia. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 2.7.4.25 | Tuberculosis |
18343960 |
Molecular modeling and dynamics studies of cytidylate kinase from Mycobacterium tuberculosis H37Rv. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
