1.8.1.B1: thioredoxin glutathione reductase
This is an abbreviated version!
For detailed information about thioredoxin glutathione reductase, go to the full flat file.
Word Map on EC 1.8.1.B1
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1.8.1.B1
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schistosoma
-
schistosomiasis
-
worm
-
mansoni
-
praziquantel
-
glutaredoxin
-
selenocysteine
-
antischistosomal
-
gssg
-
auranofin
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platyhelminth
-
flatworm
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dtnb
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fluke
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sjtgr
-
fasciola
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oxadiazole
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cysticerci
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hysteretic
-
medicine
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taenia
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trematode
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echinococcus
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granulosus
-
schistosomicidal
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crassiceps
-
gigantica
-
selenocysteine-containing
-
furoxans
-
analysis
- 1.8.1.B1
- schistosoma
- schistosomiasis
- worm
- mansoni
- praziquantel
- glutaredoxin
- selenocysteine
-
antischistosomal
- gssg
- auranofin
-
platyhelminth
- flatworm
- dtnb
- fluke
-
sjtgr
- fasciola
-
oxadiazole
- cysticerci
-
hysteretic
- medicine
-
taenia
-
trematode
-
echinococcus
- granulosus
-
schistosomicidal
- crassiceps
- gigantica
-
selenocysteine-containing
- furoxans
- analysis
Reaction
Synonyms
cTGR, DmTrxR, EgTGR, mTGR, SmTGR, TGR, TGRsec, thioredoxin glutathione reductase, thioredoxin-glutathione reductase, thioredoxin/glutathione reductase
ECTree
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KCat KM Value
KCat KM Value on EC 1.8.1.B1 - thioredoxin glutathione reductase
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3.1
2-hydroxyethyl disulfide
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at 25°C in 0.1 M potassium phosphate (pH 7.4)
0.31
-
mutant C574S, pH 7.0, temperature not specified in the publication
0.35
5,5'-dithio-bis(2-nitrobenzoic acid)
-
mutant C519S, pH 7.0, temperature not specified in the publication
1.45
5,5'-dithio-bis(2-nitrobenzoic acid)
-
wild-type, pH 7.0, temperature not specified in the publication
21
5,5'-dithiobis(2-nitrobenzoic acid)
-
cytosolic isoform, pH 7.8, temperature not specified in the publication
119
5,5'-dithiobis(2-nitrobenzoic acid)
-
at 25°C in 0.1 M potassium phosphate (pH 7.4)
2800
5,5'-dithiobis(2-nitrobenzoic acid)
-
mitochondrial isoform, pH 7.8, temperature not specified in the publication
0.38
-
mutant C574S, pH 7.0, temperature not specified in the publication
0.47
glutathione disulfide
-
mutant C519S, pH 7.0, temperature not specified in the publication
1.87
glutathione disulfide
-
wild-type, pH 7.0, temperature not specified in the publication
150
glutathione disulfide
-
cytosolic isoform, pH 7.8, temperature not specified in the publication
420
glutathione disulfide
-
mitochondrial isoform, pH 7.8, temperature not specified in the publication
28
-
cytosolic isoform, pH 7.8, temperature not specified in the publication
390
glutathione-hydroxyethyl disulfide
-
mitochondrial isoform, pH 7.8, temperature not specified in the publication
34
-
cytosolic isoform, pH 7.8, temperature not specified in the publication
58.5
NADPH
-
with GSSG as cosubstrate, at 25°C in 0.1 M potassium phosphate (pH 7.4)
510
NADPH
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with 5,5'-dithiobis(2-nitrobenzoic acid) as cosubstrate, at 25°C in 0.1 M potassium phosphate (pH 7.4)
1360
NADPH
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with glutaredoxin as cosubstrate, at 25°C in 0.1 M potassium phosphate (pH 7.4)
7900
NADPH
-
mitochondrial isoform, pH 7.8, temperature not specified in the publication
5.2
-
cytosolic isoform, pH 7.8, temperature not specified in the publication
1480
thioredoxin disulfide
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at 25°C in 0.1 M potassium phosphate (pH 7.4)