2.1.1.203: tRNA (cytosine34-C5)-methyltransferase

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For detailed information about tRNA (cytosine34-C5)-methyltransferase, go to the full flat file.

Reaction

Synonyms

5-methylcytosine RNA methyltransferase, cytosine-5 RNA methyltransferase, cytosine-5 tRNA methyltransferase, DnmA, EC 2.1.1.29, hTrm4, M5C RNA methyltransferase, NOP2/Sun domain family member 2, NSUN2, NSUN3, NSUN3 methylase, PMT1, RCMT, RNA:m5C methyltransferase, SAKI, substrate of AIM-1/Aurora kinase B

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.203 tRNA (cytosine34-C5)-methyltransferase

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Results	in table
2	Activating Compound
1744	AA Sequence
2	Application
5	Cloned(Commentary)
8	Cofactor
17	Disease/ Diagnostics
1	Expression
29	General Information
9	Localization
1	Metals/Ions
1	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
17	Organism
1	Pathway
2	pH Optimum
1	Posttranslational Modification
12	Protein Variants
1	Purification (Commentary)
2	Reaction
15	Reference
13	Source Tissue
22	Substrates and Products (Substrate)
1	Subunits
29	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Expression

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Expression on EC 2.1.1.203 - tRNA (cytosine34-C5)-methyltransferase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

expression of NSUN2 and at least three of its m5C RNA methyltransferase family members are repressed in response to oxidative stress. Rapid and strong downregulation of NSUN2 upon arsenite treatment

Homo sapiens

Q08J23

758103