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2.3.2.2: gamma-glutamyltransferase

This is an abbreviated version!
For detailed information about gamma-glutamyltransferase, go to the full flat file.

Word Map on EC 2.3.2.2

Reaction

a (5-L-glutamyl)-peptide
+
an amino acid
=
a peptide
 +
a 5-L-glutamyl amino acid

Synonyms

(5-L-glutamyl) peptide: amino-acid 5-glutamyl transferase, alpha-glutamyl transpeptidase, AngammaGT, AsGGT1, At1g69820, At4g29210, At4g39640, At4g39650, BaGGT, BaGGT42, BaGGT469, BlGGT, BlGGT13, BsGGT168, Cgl0954, eqGGT, gamma glutamyl transferase, gamma-glutamyl peptidyltransferase, gamma-glutamyl transferase, gamma-glutamyl transferase 1, gamma-glutamyl transferase 5, gamma-glutamyl transferase/transpeptidase, gamma-glutamyl transferases, gamma-glutamyl transpeptidase, gamma-glutamyl transpeptidase 1, gamma-glutamyl transpeptidase 4, gamma-glutamyl transpeptidase-1, gamma-glutamyl-transpeptidase, gamma-glutamyltransferase, gamma-glutamyltranspeptidase, gamma-GPT, gamma-GT, gamma-GTase, gamma-GTP, gammaGT, GGT, GGT A, GGT I, GGT-1, GGT1, GGT2, GGT3, GGT4, GGT5, ggtB, GGTII protein, GGTLA1, glutamyl transpeptidase, glutamyltransferase, gamma-, HGGT, L-gamma-glutamyl transpeptidase, L-gamma-glutamyltransferase, L-glutamyltransferase, More, PnGGT, SBLGGT, VvGGT3

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.2 gamma-glutamyltransferase

KI Value

KI Value on EC 2.3.2.2 - gamma-glutamyltransferase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.053
(2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)sulfinyl)butanoic acid
-
-
3.5
(2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)sulfonyl)butanoic acid
-
-
0.52
(2S)-2-amino-4-((3-((carboxymethyl)amino)-3-oxopropyl)thio)butanoic acid
-
-
0.23
(2S)-2-amino-4-((4-(((carboxymethyl)amino)carbonyl)benzyl)sulfinyl)butanoic acid
-
-
5.9
2-amino-4-(methylsulfinyl)butanoic acid
-
pH 8.0, 37°C
26.9
2-amino-4-(methylthio)butanoic acid
-
pH 8.0, 37°C
20.6
2-amino-4-cyanobutanoic acid
-
pH 8.0, 37°C
35.8
2-amino-4-phosphonobutanoic acid
-
pH 8.0, 37°C
11.1
2-amino-4-sulfobutanoic acid
-
pH 8.0, 37°C
0.053
2-amino-4-[(3-((carboxymethyl)amino)-3-oxopropyl)sulfinyl]butanoic acid
-
-
14.1
2-aminopentanedioic acid
-
pH 8.0, 37°C
0.1137
2-carboxypropylglutathione
-
-
23.2
4-aminobutyramide
-
-
12.6
4-carboxybutyramide
-
-
0.0287
4-chloro-N-[5-(4-chlorobenzyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
-
-
0.25
4-nitroaniline
O65652, Q39078, Q9M0G0
-
0.0057 - 0.0183
5-L-glutamyl-2-(2-carboxyphenyl)hydrazine
0.081 - 2.7
6-diazo-5-oxo-L-norleucine
0.016 - 0.88
acivicin
0.4
alpha-ketoglutarate-5-glutamylhydrazone
Oncornavirus
-
-
0.61
D-serine
-
in presence of borate
0.3 - 1.17
glutathione
0.00865
glutathione disulfide
-
pH 7.5, 22°C
2.3
glycine
-
-
0.0164 - 11
GSH
0.85 - 0.9
GSSG
30
hexobarbital
-
-
26.9
L-Met
-
-
5.9
L-methionine sulfoxide
-
-
1.13 - 1.58
L-Ser
0.022 - 0.3
L-serine
0.0759
N-(5-benzyl-1,3,4-thiadiazol-2-yl)-4-chlorobenzenesulfonamide
-
-
0.0743
N-[5-(4-chlorobenzyl)-1,3,4-thiadiazol-2-yl]-4-nitrobenzenesulfonamide
-
-
0.0433
N-[5-(4-chlorobenzyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
-
-
0.0738
N-[5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
-
-
0.007 - 0.021
ovothiol A
43
Phenobarbital
-
-
0.00774
S-(4-nitrobenzyl)glutathione
-
pH 7.5, 22°C
0.0103
S-hexylglutathione
-
pH 7.5, 22°C
0.0233
S-methyl glutathione
-
-
0.0079
S-Methylglutathione
-
pH 7.5, 22°C
0.0679
S-propyl glutathione
-
-
4.2 - 41.6
serine-borate
20
Thiobarbituric acid
-
-
additional information
additional information
-