2.3.2.21: cyclo(L-tyrosyl-L-tyrosyl) synthase

This is an abbreviated version!
For detailed information about cyclo(L-tyrosyl-L-tyrosyl) synthase, go to the full flat file.

Reaction

2 L-tyrosyl-tRNATyr = 2 tRNATyr +

Synonyms

CDPS, CDPS-Np, cyclo(L-tyrosyl-L-tyrosyl) synthase, cyclodipeptide synthase, cyclodityrosine synthetase, cYY synthase, Rv2275

ECTree

2 Transferases

2.3 Acyltransferases

2.3.2 Aminoacyltransferases

2.3.2.21 cyclo(L-tyrosyl-L-tyrosyl) synthase

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Results	in table
2	AA Sequence
3	Application
2	Cloned(Commentary)
1	Crystallization (Commentary)
11	General Information
4	Natural Substrates/ Products (Substrates)
10	Organism
3	Pathway
8	Protein Variants
2	Purification (Commentary)
3	Reaction
8	Reference
12	Substrates and Products (Substrate)
25	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.2.21 - cyclo(L-tyrosyl-L-tyrosyl) synthase

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2 L-tyrosyl-tRNATyr

2 tRNATyr + cyclo(L-tyrosyl-L-tyrosyl)

Mycobacterium tuberculosis

P9WPF9

759890

2 L-tyrosyl-tRNATyr

tRNATyr + cyclo(L-tyrosyl-L-tyrosyl)

Nocardiopsis prasina

759643

L-tyrosyl-tRNATyr + L-phenylalanyl-tRNAPhe

tRNATyr + tRNAPhe + cyclo(L-tyrosyl-L-phenylalanyl)

Nocardiopsis prasina

759643

additional information

Mycobacterium tuberculosis

P9WPF9

Rv2275 is established as a CDPS that catalyzes formation of cyclo(L-tyrosyl-L-tyrosyl) as its major product, along with a handful of minor products containing tyrosine

759890