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2.4.1.68: glycoprotein 6-alpha-L-fucosyltransferase

This is an abbreviated version!
For detailed information about glycoprotein 6-alpha-L-fucosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.68

Reaction

GDP-beta-L-fucose
+
N4-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc]-L-asparaginyl-[protein]
=
GDP
+
N4-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc]-L-asparaginyl-[protein]

Synonyms

6FucT, alfC, alpha(1,6)FT, alpha(1,6)fucosyltransferase, alpha-1,6-fucosyltransferase, alpha-6-fucosyltransferase, alpha1,6-fucosyltransferase, alpha1,6-FucT, alpha1,6FucT, alpha1-6,fucosyltransferase, alpha1-6FucT, alpha6FucT, BN194_28780, fucosyltransferase 8, fucosyltransferase, guanosine diphosphofucose-glycoprotein, FUT8, GDP-fucose glycoprotein fucosyltransferase, GDP-fucose-glycoprotein fucosyltransferase, GDP-L-fuc:N-acetyl-beta-D-glucosaminide alpha1-6fucosyltransferase, GDP-L-fucose-glycoprotein fucosyltransferase, GDP-L-fucose:2-acetamido-2-deoxy-beta-D-glucoside 6-alpha-L-fucosyltransferase, GDPfucose glycoprotein fucosyltransferase, glycoprotein fucosyltransferase, guanosine diphosphofucose-glycoprotein fucosyltransferase, NodZ, NodZ fucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.68 glycoprotein 6-alpha-L-fucosyltransferase

Source Tissue

Source Tissue on EC 2.4.1.68 - glycoprotein 6-alpha-L-fucosyltransferase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
14 splice variants of the alpha6-fucosyltransferase gene are expressed early in human embryos
Manually annotated by BRENDA team
-
CD34+ cell, activity of 6FucT increases ahead of, and thereafter concomitantly with, cells expressing the CD41a antigen. When the CD41a+ subpopulation of cells is immunoselected (using anti-CD61 i.e. anti GpIIIa antibodies), its 6FucT activity increases proportionally to the yield of DC61+ cells
Manually annotated by BRENDA team
-
heavy load of 6FucT
Manually annotated by BRENDA team