2.4.1.83: dolichyl-phosphate beta-D-mannosyltransferase

This is an abbreviated version!
For detailed information about dolichyl-phosphate beta-D-mannosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.83

2.4.1.83

n-linked

n-glycosylation

glycosylphosphatidylinositol

lipid-linked

reesei

dolichol-phosphate-mannose

asparagine-linked

amphomycin

dolichol-linked

glc3man9glcnac2-pp-dol

mannoproteins

c-mannosylation

medicine

drug development

Reaction

Synonyms

AglD, bDPM1, D-P-M, Dol-P Man synthase, Dol-P-Man synthase, Dol-P-Man synthase1, Dol-P-Man-synthase, Dol-P-Mansynthase, Dol-PMan synthase, dolichol phosphate mannose synthase, dolichol phosphoryl mannose synthase, dolichol-P-mannose synthase, dolicholphosphate mannose synthase, dolichyl mannosyl phosphate synthase, dolichyl phosphate mannosyltransferase, dolichyl-phosphate mannose synthase, dolichyl-phosphate mannosyltransferase, dolichyl-phospho-mannose synthase, dolichylphosphate mannose synthase, DPM, DPM synthase, DPM1, DPMS, DPMS1, GDP-Man:DolP mannosyltransferase, GDP-mannose-dolichol phosphate mannosyltransferase, GDPMan:DolP mannosyltransferase, GDPmannose-dolichylmonophosphate mannosyltransferase, GDPmannose:dolichyl-phosphate mannosyltransferase, mannosylphospho dolichol synthase, mannosylphosphodolichol synthase, mannosylphosphoryldolichol synthase, mannosyltransferase, guanosine diphosphomannose-dolichol phosphate, MPD synthase, PF0058, Pfdpm1, PfDPMS, PH0051

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.83 dolichyl-phosphate beta-D-mannosyltransferase

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Results	in table
17	Activating Compound
5205	AA Sequence
4	Application
1	CAS Registry Number
16	Cloned(Commentary)
2	Crystallization (Commentary)
22	Disease/ Diagnostics
3	Expression
28	General Information
4	General Stability
53	Inhibitors
7	Ki Value [mM]
39	KM Value [mM]
33	Localization
23	Metals/Ions
6	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
67	Organism
9	Pathway
12	pH Optimum
2	pH Range
5	Posttranslational Modification
18	Protein Variants
16	Purification (Commentary)
6	Reaction
1	Reaction Type
62	Reference
27	Source Tissue
7	Specific Activity [micromol/min/mg]
8	Storage Stability
78	Substrates and Products (Substrate)
9	Subunits
77	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
9	Turnover Number [1/s]

Purification

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Purification on EC 2.4.1.83 - dolichyl-phosphate beta-D-mannosyltransferase

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5 entries

DEAE-cellulose column chromatography, gel filtration

Arabidopsis thaliana

723410

His-tag fusion protein purified using ProBond purification system, more than 97% pure

Bos taurus

703922

one-step purification

Trichoderma reesei

489455

partial

Entamoeba histolytica

489447

recombinant His-tagged wild-type and mutant enzymes from Escherichia coli strain C41(DE3) membranes by solubilization with 1% n-dodecyl-beta-D-maltoside in presence of 5% v/v glycerol, nickel affinity chromatography, followed by gel filtration and ultrafiltration. Mutant variant DELTA230-352 is prepared as two fractions, one purified from the membrane fraction (DELTA230-352 m) and one from the aqueous phase (DELTA230-352 s)

Pyrococcus furiosus

Q8U4M3

757762

solubilized with Triton X-100 and purified to homogeneity

Pyrococcus horikoshii

692257