2.4.1.87: N-acetyllactosaminide 3-alpha-galactosyltransferase

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For detailed information about N-acetyllactosaminide 3-alpha-galactosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.87

2.4.1.87

epitope

rejection

xenotransplantation

porcine

hyperacute

primates

anti-gal

glycosyltransferases

gene-knockout

xenoantigens

xenogeneic

baboon

pig-to-human

galalpha1,3gal

alphagal

galalpha1-3galbeta1-4glcnac-r

galt-ko

xenoreactive

alpha-galactosylated

pig-to-primate

non-gal

anti-alphagal

b4galnt2

forssman

xenoantibodies

decay-accelerating

simplicifolia

anti-pig

alpha1,2-fucosyltransferase

pig-to-baboon

n-glycolylneuraminic

neu5gc

medicine

diagnostics

synthesis

Reaction

beta-D-galactosyl-(1->4)-beta-N-acetyl-D-glucosaminyl-R

alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R

Synonyms

alpha(1,3)GT, alpha-1,3-galactosyltransferase, alpha-1,3galactosyltransferase, alpha-D-galactosyltransferase, alpha-galactosyltransferase, alpha1,3-galactosyltransferase, alpha1,3-GalT, alpha1,3galactosyltransferase, alpha1,3GalT, alpha1,3GT, alpha3-galactosyltransferase, alpha3Gal-T, alpha3GalT, alpha3GT, beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase, blood group glycosyltransferase, EC 2.4.1.124, EC 2.4.1.151, galactosyltransferase, uridine diphosphogalactose-acetyllactosamine, galactosyltransferase, uridine diphosphogalactose-acetyllactosamine alpha1-->3-, galactosyltransferase, uridine diphosphogalactose-galactosylacetylglucosamine alpha-1,3-, galactosyltransferase, uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide, GALT, GGTA1, glucosaminylglycopeptide alpha-1,3-galactosyltransferase, GTB, iGb3 synthase, iGb3S, N-acetyllactoseaminide 3-alpha-D-galactosyltransferase, one, three-galactosyltransferase, Otg1p, Otg2p, Otg3p, UDP-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase, UDP-Gal:N-acetyllactoseaminide alpha(1,3)-galactosyltransferase, UDP-galactose beta galactosyl alpha1,3-galactosyltransferase, UDP-galactose beta-galactosyl alpha-1,3-galactosyltransferase, UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase, UDP-galactose-acetyllactoseamine alpha-D-galactosyltransferase, UDP-galactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase, UDP-galactose:N-acetyllactoseaminide 3-alpha-D-galactosyltransferase, UDP-GalN-acetyllactoseaminide alpha-1,3-D-UDP-GalGalbeta1-->4GlcNAC-R alpha1-->3-galactosyltransferase, UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase, uridine diphosphogalactose-acetyllactosamine alpha1-->3-galactosyltransferase, uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase, WciN, wclR

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.87 N-acetyllactosaminide 3-alpha-galactosyltransferase

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Results	in table
4	Activating Compound
46	AA Sequence
12	Application
4	CAS Registry Number
29	Cloned(Commentary)
1	Cofactor
9	Crystallization (Commentary)
95	Disease/ Diagnostics
30	General Information
2	General Stability
9	Inhibitors
14	kcat/KM [mM/s]
2	Ki Value [mM]
69	KM Value [mM]
7	Localization
27	Metals/Ions
10	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
72	Organism
4	Pathway
28	PDB ID
10	pH Optimum
2	pH Range
54	Protein Variants
11	Purification (Commentary)
4	Reaction
1	Reaction Type
67	Reference
26	Source Tissue
13	Specific Activity [micromol/min/mg]
2	Storage Stability
106	Substrates and Products (Substrate)
7	Subunits
136	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
27	Turnover Number [1/s]

Purification

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Purification on EC 2.4.1.87 - N-acetyllactosaminide 3-alpha-galactosyltransferase

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2 entries

calf

Bos taurus

489466

centrifugation of cell culture, pellet lysed with EasyLyse, loaded onto Ni-chelate column, washing and elution with 20 mM Tris-HCl, pH 7.9, containing NaCl and imidazole

Bos taurus

P14769

708604

different detergents for solubilization, best with Triton CF-54

Oryctolagus cuniculus

489462

Ehrlich ascites carcinoma cells

Mus musculus

489463, 489471

HisTrap HP column chromatography

Streptococcus pneumoniae

721667

partial

2 entries