2.4.2.12: nicotinamide phosphoribosyltransferase

This is an abbreviated version!
For detailed information about nicotinamide phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

eNAMPT, extracellular nicotinamide phosphoribosyltrasferase, iNAMPT, Nam phosphoribosyltransferase, NAmPRTase, Nampt, Nampt/PBEF/Visfatin, Nampt/visfatin, NAMPTA, NAMPTB, NAPRT, nicotinamide mononucleotide pyrophosphorylase, nicotinamide mononucleotide synthetase, nicotinamide phosphoribosyl transferase, nicotinamide phosphoribosyltransferase, nicotinamide phosphoribosyltransferase/Visfatin, NMN pyrophosphorylase, NMN synthetase, NMPRTase, PBEF, phosphoribosyltransferase, nicotinamide, pre-B cell colony enhancing factor, pre-B cell colony enhancing factor(PBEF), pre-B cell colony-enhancing factor, pre-B cell colony-enhancing factor (PBEF), pre-B cell colony-enhancing factor 1, pre-B colony enhancing factor, pre-B-cell colony enhancing factor, pre-B-cell colony-enhancing factor, Visfatin

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.12 nicotinamide phosphoribosyltransferase

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Results	in table
5	Activating Compound
1361	AA Sequence
9	Application
1	CAS Registry Number
19	Cloned(Commentary)
6	Cofactor
6	Crystallization (Commentary)
8669	Disease/ Diagnostics
11	Expression
27	General Information
2	General Stability
230	IC50 Value
417	Inhibitors
66	Ki Value [mM]
24	KM Value [mM]
13	Localization
9	Metals/Ions
8	Molecular Weight [Da]
58	Natural Substrates/ Products (Substrates)
76	Organism
3	Pathway
177	PDB ID
5	pH Optimum
3	pH Range
3	pH Stability
1	pI Value
2	Posttranslational Modification
27	Protein Variants
15	Purification (Commentary)
2	Reaction
7	Reaction Type
75	Reference
193	Source Tissue
12	Specific Activity [micromol/min/mg]
5	Storage Stability
80	Substrates and Products (Substrate)
15	Subunits
136	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
2	Temperature Stability [°C]
10	Turnover Number [1/s]

General Stability

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General Stability on EC 2.4.2.12 - nicotinamide phosphoribosyltransferase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

bovine serum albumin, glutathione, cysteine, DTT, EDTA, cystine or H2O2 does not stabilize during storage

Rattus norvegicus

-

489738

freeze-thawing inactivates

Homo sapiens

-

489740