2.4.2.2: pyrimidine-nucleoside phosphorylase
This is an abbreviated version!
For detailed information about pyrimidine-nucleoside phosphorylase, go to the full flat file.
Reaction
Synonyms
AmPyNP, BbPyNP, BfPyNP, BsPyNP, deoA, EC 2.4.2.23, GsPyNP, GtPyNP, LpPyNP, nucleoside phosphorylase, PDP, phosphorylase, pyrimidine nucleoside, Py-NPase, PYNP, pynpase, pyrimidine nucleoside phosphorylase, pyrimidine ribonucleoside phosphorylase, pyrimidine-nucleoside phosphorylase, pyrimidine/purine nucleoside phosphorylase, TTHA1771, TtPyNP, udp, UPase
ECTree
Advanced search results
Application
Application on EC 2.4.2.2 - pyrimidine-nucleoside phosphorylase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
medicine
-
the cytostatic and antiviral activity of pyrimidine nucleoside analogues is markedly decreased by a Mycoplasma hyorhinis infection and the phosphorolytic activity of the mycoplasmas is responsible for this
synthesis
synthesis
-
overexpression of enzyme in Escherichia coli, medium optimization and presence of uridine and 5-fluorouracil results in conversion of more than 90% of uridine to 5-fluorouridine by the cells
synthesis
the enzyme is useful in biocatalytic production of 2,6-dichloropurine 2'-deoxyriboside and 6-chloro-2-fluoropurine 2'-deoxyriboside
synthesis
the enzyme is useful in biocatalytic production of 2-chloro-2'-deoxyadenosine (cladribine), adenine-arabinoside, 2-fluoroadenine arabinoside, and 5-methyluridine
synthesis
the enzyme is useful in biocatalytic production of 2-chloroadenine riboside, 2-fluoroadenine riboside, 2,6-diaminopurine 2'-deoxyriboside, 2-chloro-2'-deoxyadenosine, 2-fluoro-2'-deoxyadenosine, 2'-deoxy-2'-fluoroadenosine, 2'-deoxy-2'-fluoro-arabinofuranosyl adenine, 2,6-diaminopurine arabinoside, 2,6-dichloropurine arabinoside, 6-chloro-2-fluoropurine arabinoside, and 5-iododeoxyuridine
synthesis
-
during enzymatic synthesis of adenine arabinoside from adenine and uracil arabinoside with wet cells of Klebsiella aerogenes induced by cytidine or CMP, the reaction time can be shortened from 36 to 6 h
synthesis
-
overexpression of enzyme in Escherichia coli, medium optimization and presence of uridine and 5-fluorouracil results in conversion of more than 90% of uridine to 5-fluorouridine by the cells
-