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2.4.2.2: pyrimidine-nucleoside phosphorylase

This is an abbreviated version!
For detailed information about pyrimidine-nucleoside phosphorylase, go to the full flat file.

Word Map on EC 2.4.2.2

Reaction

2'-deoxyuridine
+
phosphate
=
Uracil
 +
2-deoxy-alpha-D-ribose 1-phosphate

Synonyms

AmPyNP, BbPyNP, BfPyNP, BsPyNP, deoA, EC 2.4.2.23, GsPyNP, GtPyNP, LpPyNP, nucleoside phosphorylase, PDP, phosphorylase, pyrimidine nucleoside, Py-NPase, PYNP, pynpase, pyrimidine nucleoside phosphorylase, pyrimidine ribonucleoside phosphorylase, pyrimidine-nucleoside phosphorylase, pyrimidine/purine nucleoside phosphorylase, TTHA1771, TtPyNP, udp, UPase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.2 pyrimidine-nucleoside phosphorylase

Specific Activity

Specific Activity on EC 2.4.2.2 - pyrimidine-nucleoside phosphorylase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.46
purified recombinant His-tagged enzyme, pH 7.0, 25°C
11.2
substrate deoxyuridine, pH 7.5, temperature not specified in the publication
28.4
purified recombinant enzyme, pH 8.0, 50°C, substrate uridine
37.5
purified recombinant enzyme, pH 8.0, 50°C, substrate uridine
43.3
purified recombinant enzyme, pH 8.5, 50°C, substrate uridine
45
-
purified recombinant enzyme
5.9
substrate thymidine, pH 7.5, temperature not specified in the publication
55.8
-
purified recombinant enzyme, pH 8.0, 50°C, substrate uridine
8.1
substrate uridine, pH 7.5, temperature not specified in the publication
98.3
purified recombinnat enzyme, pH 8.5, 50°C, substrate uridine
additional information