2.4.2.48: tRNA-guanine15 transglycosylase

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For detailed information about tRNA-guanine15 transglycosylase, go to the full flat file.

Reaction

Synonyms

archaeosine tRNA-guanine transglycosylase, archaeosine tRNAguanine transglycosylase, ArcTGT, multisite-specific archaeosine tRNA-guanine transglycosylase, Ta1493, TGT, transfer ribonucleic acid guanine15 transglycosylase, tRNA guanine15 transglycosidase, tRNA-guanine transglycosylase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.48 tRNA-guanine15 transglycosylase

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Results	in table
1970	AA Sequence
6	Cloned(Commentary)
2	Crystallization (Commentary)
3	General Information
2	kcat/KM [mM/s]
3	KM Value [mM]
4	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
17	Organism
2	Pathway
4	pH Optimum
1	Protein Variants
5	Purification (Commentary)
1	Reaction
14	Reference
3	Specific Activity [micromol/min/mg]
17	Substrates and Products (Substrate)
5	Subunits
23	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.4.2.48 - tRNA-guanine15 transglycosylase

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SYSTEMATIC NAME

IUBMB Comments

tRNA-guanine15:7-cyano-7-carbaguanine tRNA-D-ribosyltransferase

Archaeal tRNAs contain the modified nucleoside archaeosine at position 15. This archaeal enzyme catalyses the exchange of guanine at position 15 of tRNA with the base preQ0, which is ultimately modified to form the nucleoside archaeosine (cf. EC 2.6.1.97) [1].