Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.5.1.108: 2-(3-amino-3-carboxypropyl)histidine synthase

This is an abbreviated version!
For detailed information about 2-(3-amino-3-carboxypropyl)histidine synthase, go to the full flat file.

Word Map on EC 2.5.1.108

Reaction

S-adenosyl-L-methionine
+
L-histidine-[translation elongation factor 2]
=
S-methyl-5'-thioadenosine
 +
2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2]

Synonyms

diphthamide biosynthesis protein 2, diphthine synthase, Dph1-Dph2, Dph2, DPH4, PhDph2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.108 2-(3-amino-3-carboxypropyl)histidine synthase

Crystallization

Crystallization on EC 2.5.1.108 - 2-(3-amino-3-carboxypropyl)histidine synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
enzyme in complex with elongation factor 2, hanging drop vapor diffusion method, using 100 mM Tris (pH 7.2), 200 mM MgSO4, and 21% (w/v) PEG 400
crystal structure at 2.3 A resolution
hanging-drop vapour-diffusionmethod, X-ray crystal structure at 2.3 A resolution using selenomethionine single-wavelength anomalous diffraction phasing