2.5.1.86: trans,polycis-decaprenyl diphosphate synthase
This is an abbreviated version!
For detailed information about trans,polycis-decaprenyl diphosphate synthase, go to the full flat file.
Word Map on EC 2.5.1.86
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2.5.1.86
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ubiquinone
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isoprenoid
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prenylation
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isoprene
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geranyl
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octaprenyl
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solanesyl
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prenyltransferases
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ubiquinone-10
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gluconobacter
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suboxydans
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corticorubral
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rubrospinal
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1-deoxy-d-xylulose
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drug development
- 2.5.1.86
- ubiquinone
-
isoprenoid
-
prenylation
- isoprene
-
geranyl
-
octaprenyl
-
solanesyl
- prenyltransferases
- ubiquinone-10
-
gluconobacter
- suboxydans
-
corticorubral
-
rubrospinal
- 1-deoxy-d-xylulose
- drug development
Reaction
+ 7 isopentenyl diphosphate = 7 diphosphate +
Synonyms
cis-decaprenyl diphosphate synthase, decaprenyl diphosphate synthase, decaprenyl diphosphate synthase 1, decaprenyl diphosphate synthase 2, DPP synthase, DPPS, DPS1, long-chain prenyl diphosphate synthase, MtDPPS, polyprenyl diphosphate synthase, Rv2361c, SlDPS, Z-decaprenyl-diphosphate synthase
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 2.5.1.86 - trans,polycis-decaprenyl diphosphate synthase
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REACTION DIAGRAM
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
(2Z,6E)-farnesyl diphosphate + isopentenyl diphosphate
diphosphate + trans,octacis-decaprenyl diphosphate
additional information
?
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the enzyme can utilize geranyl, farnesyl or geranylgeranyl diphosphates in the synthesis of C45 and C50 prenyl diphosphates
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-
?
7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate
the catalytic efficiency is greatest when (2Z,6E)-farnesyl diphosphate is used as the allylic acceptor, suggesting that this is the natural substrate in vivo
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-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate
the enzyme is involved in the biosynthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of essential mycobacterial cell wall components, such as the mycolyl-arabinogalactan-peptidoglycan complex and lipoarabinomannan
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-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate
the catalytic efficiency is greatest when (2Z,6E)-farnesyl diphosphate is used as the allylic acceptor, suggesting that this is the natural substrate in vivo
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-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate
the enzyme is involved in the biosynthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of essential mycobacterial cell wall components, such as the mycolyl-arabinogalactan-peptidoglycan complex and lipoarabinomannan
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate
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the enzyme is involved in decaprenyl phosphate synthesis, that is important in the rate of bacterial growth and the synthesis of cell wall components
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-
?
7 diphosphate + trans,octacis-decaprenyl diphosphate
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-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
Bullera alba NBRC 1192
-
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
Cystobasidium minutum NBRC 0387
-
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
-
?
(2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + trans,octacis-decaprenyl diphosphate
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-
-
-
?
diphosphate + trans,octacis-decaprenyl diphosphate
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-
-
?
(2Z,6E)-farnesyl diphosphate + isopentenyl diphosphate
diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
-
?
(2Z,6E)-farnesyl diphosphate + isopentenyl diphosphate
diphosphate + trans,octacis-decaprenyl diphosphate
-
-
-
?