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2.6.1.57: aromatic-amino-acid transaminase

This is an abbreviated version!
For detailed information about aromatic-amino-acid transaminase, go to the full flat file.

Word Map on EC 2.6.1.57

Reaction

an aromatic amino acid
+
2-oxoglutarate
=
an aromatic oxo acid
+
L-glutamate

Synonyms

AAT, AAT I-III, AAT1, aminotransferase, aromatic amino acid, ArAT, ArAT-I, ArAT-ITL, ArATPf, ArATPh, Aro8, ARO9, AroAT, AroAT II, AroATEs, AroH, arom. amino acid transferase, arom.-amino-acid transaminase, aromatic amino acid aminotransferase, aromatic amino acid transaminase, aromatic amino transferase I, aromatic aminotransferase, aromatic aminotransferase AT-1, aromatic aminotransferase AT-2, aromatic aminotransferase II, aromatic L-amino acid transaminase, aromatic-amino-acid aminotransferase, aromatic-amino-acid:2-oxoglutarate transaminase, AT-1, AT-2, AT-IA, At1g80360, bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase, CaAro8p, CaAro9p, CaYer152Cp, eAroATEs, F5I6.11, hisC1, indole severe sensitive 1, ISS1, More, pdArAT, pdAroAT, PH1371, phhC, PjAT, SmAroAT, TyrB, TyrB-2, VAT1, Yer152, Yer152C

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.57 aromatic-amino-acid transaminase

KM Value

KM Value on EC 2.6.1.57 - aromatic-amino-acid transaminase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2
2-oxo-4-methylpentanoate
-
pH 7.6, 37°C
0.1 - 0.13
2-oxoadipate
0.14 - 38
2-oxoglutarate
0.059
3-(4-hydroxyphenyl)pyruvate
pH 8.0, 25°C, cosubstrate aspartate
0.026 - 0.05
4-hydroxyphenylpyruvate
0.016 - 4.28
alpha-aminoadipate
0.33
alpha-ketomethiobutyrate
7.04
glyoxylate
pH 7.0, 22°C
0.8
hydroxyphenylpyruvate
-
-
0.06 - 0.1
Indolepyruvate
0.36
L-5-fluorotryptophan
-
-
1.2
L-5-methyltryptophan
-
-
0.45
L-arogenate
-
pH 8.6, 37°C, AAT I
0.079 - 8.4
L-aspartate
12.22
L-cysteine
at pH 7.4 and 30°C
0.28 - 10
L-glutamate
7
L-glutamine
-
pH 8.6, 37°C, AAT I
0.35 - 70
L-histidine
9
L-kynurenine
-
pH 7.4, 25°C, recombinant enzyme, with cosubstrate 2-oxoglutarate
4 - 7.1
L-leucine
1.5 - 5
L-methionine
0.05 - 16.6
L-phenylalanine
0.095 - 16.6
L-tryptophan
0.042 - 15
L-tyrosine
0.12 - 5.1
oxaloacetate
2.18
phenylalanine
0.01 - 0.083
phenylpyruvate
0.08
prephenate
-
pH 8.6, 37°C, AAT I
0.001 - 0.025
pyridoxal 5'-phosphate
3.59 - 8.8
pyruvate
additional information
additional information
-