2.7.1.151: inositol-polyphosphate multikinase

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For detailed information about inositol-polyphosphate multikinase, go to the full flat file.

Word Map on EC 2.7.1.151

2.7.1.151

phosphatidylinositol

phospholipase

phosphoinositide

4,5-bisphosphate

4-phosphate

5-phosphatase

1,3,4,5-tetrakisphosphate

bacteriorhodopsin

insp3

pip2

ptdins4,5p2

4-kinase

hexakisphosphate

pikfyve

ptdins4p

pentakisphosphate

1,3,4-trisphosphate

3hinositol

phosphatidylinositol-4-phosphate

photocycle

diphosphoinositol

inositide

3,4,5-trisphosphate

5/6-kinase

polyphosphoinositide

medicine

light-driven

arf6

agriculture

Reaction

1D-myo-inositol 1,4,5,6-tetrakisphosphate

1D-myo-inositol 1,3,4,5,6-pentakisphosphate

Synonyms

1,3,4,6-tetrakisphosphate 5-kinase, 5-kinase, Arg82, ArgRIII, ARGSIII, AtIpk2a, AtIpk2b, AtIpk2beta, HsIPMK, Impk, inositol 1,4,5-trisphosphate 3-kinase, inositol phosphate multikinase, inositol phosphate multikinase 2, inositol polyphosphate 6-/3-kinase, inositol polyphosphate kinase, inositol polyphosphate multikinase, Ins(1,4,5)P3 3-kinase, InsP4 5-kinase, IP3 3-kinase, IP3/IP4 6-/3-kinase, IP3K, IPK, Ipk2, Ipk2/Impk/IP3K, Ipk2a, Ipk2beta/IP3K, IPKII, IPMK, ITPK1, Kcs1, Kcs1p, More, phosphoinositol kinase, PI3K, StIPMK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.151 inositol-polyphosphate multikinase

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Results	in table
5	Activating Compound
564	AA Sequence
8	Application
1	CAS Registry Number
26	Cloned(Commentary)
23	Cofactor
4	Crystallization (Commentary)
90	Disease/ Diagnostics
16	General Information
1	General Stability
7	IC50 Value
15	Inhibitors
8	kcat/KM [mM/s]
2	Ki Value [mM]
31	KM Value [mM]
16	Localization
21	Metals/Ions
6	Molecular Weight [Da]
79	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
46	Organism
5	Pathway
18	PDB ID
11	pH Optimum
9	Posttranslational Modification
36	Protein Variants
11	Purification (Commentary)
4	Reaction
9	Reaction Type
45	Reference
52	Source Tissue
17	Specific Activity [micromol/min/mg]
134	Substrates and Products (Substrate)
8	Subunits
109	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Stability [°C]

Specific Activity

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Specific Activity on EC 2.7.1.151 - inositol-polyphosphate multikinase

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0.0085

Gallus gallus

393218

0.37

Oryza sativa

substrate inositol monophosphate

393219

0.45

Homo sapiens

Q8NFU5

purified recombinant enzyme, 1D-myo-inositol 1,3,4,5,6-pentakisphosphate formation from 1D-myo-inositol 1,4,5-trisphosphate, 0.5 mM ATP

660946

0.49

Oryza sativa

substrate inositol diphosphate

393219

0.5

Rattus norvegicus

partially purified enzyme

663233

0.7

Saccharomyces cerevisiae

partially purified enzyme

1.8

1.84

substrate inositol triphosphate

393219

1.92

Oryza sativa

substrate inositol tetrakisphosphate

393219

2.5

Homo sapiens

recombinant wild-type enzyme, substrate 1D-myo-inositol 1,4,5-trisphosphate

662346

3.08

Oryza sativa

substrate inositol pentakisphosphate

393219

5.5

Homo sapiens

recombinant deletion mutant enzyme, substrate 1D-myo-inositol 1,4,5-trisphosphate

662346

additional information

7 entries