2.7.7.14: ethanolamine-phosphate cytidylyltransferase

This is an abbreviated version!
For detailed information about ethanolamine-phosphate cytidylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.14

2.7.7.14

phosphatidylethanolamine

phospholipid

cdp-ethanolamine

diacylglycerols

kennedy

cdp-choline

ctp:phosphocholine

phosphocholine

3hethanolamine

ptdetn

ethanolaminephosphotransferase

14cethanolamine

drug development

Reaction

Synonyms

CTP-phosphoethanolamine cytidylyltransferase, CTP:ethanolaminephosphate cytidylyltransferase, CTP:phosphoethanolamine CT, CTP:phosphoethanolamine cytidylyltransferase, CTP:phosphoethanolamine cytidylyltransferase gene, cytidylyltransferase, ethanolamine phosphate, ECT, ET, ethanolamine phosphate cytidylyltransferase, ethanolamine-phosphate cytidylyltransferase, Pcyt2, Pcyt2alpha, Pcyt2beta, PECT1, phosphoethanolamine cytidyltransferase, phosphoethanolamine cytidylyltransferase, phosphorylethanolamine transferase, Tb11.01.5730

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.7 Nucleotidyltransferases

2.7.7.14 ethanolamine-phosphate cytidylyltransferase

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Results	in table
15	Activating Compound
5104	AA Sequence
1	Application
1	CAS Registry Number
12	Cloned(Commentary)
1	Crystallization (Commentary)
83	Disease/ Diagnostics
16	Expression
37	General Information
5	General Stability
30	Inhibitors
4	Ki Value [mM]
34	KM Value [mM]
21	Localization
10	Metals/Ions
14	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
349	Organism
7	Pathway
2	PDB ID
11	pH Optimum
1	pH Range
1	pH Stability
1	pI Value
1	Posttranslational Modification
10	Protein Variants
13	Purification (Commentary)
3	Reaction
1	Reaction Type
43	Reference
92	Source Tissue
4	Specific Activity [micromol/min/mg]
2	Storage Stability
62	Substrates and Products (Substrate)
11	Subunits
69	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
11	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.7.7.14 - ethanolamine-phosphate cytidylyltransferase

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1-Aminoethylphosphonate

Rattus norvegicus

inhibitory power stimulated by Mg2+; noncompetitive to phosphorylethanolamine

642884

2-aminoethylphosphonate

Rattus norvegicus

competitive to phosphorylethanolamine; inhibitory power stimulated by Mg2+

642884

3-Aminopropylphosphonate

Rattus norvegicus

competitive to phosphorylethanolamine; inhibitory power stimulated by Mg2+

642884

aminoimidazole-4-carboxamide

CDP-ethanolamine

CTP

at concentrations exceeding that of Mg2+

diphosphate

iodoacetamide

NEM

oleate

PCMB

phosphocholine

phosphodimethylethanolamine

Rattus norvegicus

weak, competitive to phosphoethanolamine

642887

phosphoethanolamine methyl-analogues

6 entries

phosphomonomethylethanolamine

Rattus norvegicus

weak, competitive to phosphoethanolamine

642887

Sphingosine/phosphatidylcholine vesicles

Rattus norvegicus

inhibit cytosolic and purified enzyme

642885

additional information

Rattus norvegicus

overactivation of the NMDA receptor in neurons inhibits the enzyme, membrane damage by NMDA receptor is preceeded by inhibition of phospholipid synthesis

642888