Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
1,3-dihydroxybenzene + NADPH + H+ + O2
? + NADP+ + H2O
-
50.12% activity compared to phenol
-
-
?
2 2-cresol + NADPH + O2
3-methylcatechol + 4-methylcatechol + NADP+ + H2O
-
-
-
-
?
2 2-xylene + 2 NADPH + 2 H+ + 2 O2
2,3-dimethylphenol + 3,4-dimethylphenol + 2 NADP+ + 2 H2O
2 ethynylbenzene + NADPH + 3 O2
2-ethynylphenol + 2-hydroxy-6-oxo-octa-2,4-dien-7-ynoic acid + NADP+ + H2O
2,3,4-trifluorophenol + O2 + NADPH
?
-
-
-
-
?
2,3,5,6-tetrafluorophenol + O2 + NADPH
3,4,6-trifluoro-2-benzoquinone + NADP+ + F-
-
-
-
?
2,3,5,6-tetrafluorophenol + O2 + NADPH
?
-
-
-
-
?
2,3,5-trifluorophenol + O2 + NADPH
?
-
-
-
-
?
2,3,6-trifluorophenol + O2 + NADPH
?
-
-
-
-
?
2,3-difluorophenol + O2 + NADPH
?
-
-
-
-
?
2,4-dichlorophenol + NADPH + H+ + O2
2,4-dichlorocatechol + NADP+ + H2O
2,4-difluorophenol + O2 + NADPH
?
-
-
-
-
?
2,5-difluorophenol + O2 + NADPH
?
-
-
-
-
?
2,6-difluorophenol + O2 + NADPH
?
-
-
-
-
?
2-amino-3-methylphenol + O2 + NADPH
?
-
-
-
-
?
2-aminophenol + NADPH + H+ + O2
2-aminocatechol + NADP+ + H2O
2-aminophenol + O2 + NADPH
?
2-chlorophenol + NADPH + H+ + O2
2-chlorocatechol + NADP+ + H2O
2-chlorophenol + O2 + NADPH
?
2-cresol + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
2-ethylphenol + NADPH + O2
3-ethyl-benzene-1,2-diol + NADP+ + H2O
2-fluorophenol + O2 + NADPH
?
-
-
-
-
?
2-hydroxybenzoic acid + NADPH + H+ + O2
? + NADP+ + H2O
-
15.97% activity compared to phenol
-
-
?
2-hydroxyphenol + NADPH + H+ + O2
?
2-methyl-phenol + O2 + NADPH
?
2-methylindole + NADPH + O2
?
-
-
-
-
?
2-naphthol + NADPH + H+ + O2
? + NADP+ + H2O
-
9.75% activity compared to phenol
-
-
?
2-nitrophenol + NADPH + H+ + O2
?
3 toluene + 3 NADPH + 3 H+ + 3 O2
2-cresol + 3-cresol + 4-cresol + 3 NADP+ + 3 H2O
3,4,5-trifluorophenol + O2 + NADPH
?
-
-
-
-
?
3,4-difluorophenol + O2 + NADPH
?
-
-
-
-
?
3,4-dimethylphenol + NADH + H+ + O2
1,2-dihydroxy-3,4-dimethylbenzene + NAD+ + H2O
3,4-dimethylphenol + NADPH + O2
?
3,5-difluorophenol + O2 + NADPH
?
-
-
-
-
?
3-aminophenol + NADPH + H+ + O2
3-aminocatechol + NADP+ + H2O
-
-
-
-
?
3-aminophenol + O2 + NADPH
?
3-chloro-4-fluorophenol + O2 + NADPH
?
-
-
-
-
?
3-chlorophenol + NADH + H+ + O2
4-chlorocatechol + NAD+ + H2O
3-chlorophenol + O2 + NADPH
?
3-cresol + NADPH + H+ + O2
3-methylcatechol + NADP+ + H2O
3-cresol + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
3-cresol + NADPH + O2
3-methylcatechol + 4-methylcatechol + NADP+ + H2O
-
-
-
-
?
3-cyanoindole + NADPH + O2
?
-
substrate only of strain KL28
-
-
?
3-ethylphenol + NADH + H+ + O2
4-ethylcatechol + NAD+ + H2O
3-fluorophenol + O2 + NADPH
?
3-hydroxybenzaldehyde + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
3-hydroxybenzoic acid + NADPH + H+ + O2
? + NADP+ + H2O
-
18.53% activity compared to phenol
-
-
?
3-hydroxyphenol + NADPH + H+ + O2
?
3-hydroxyphenol + O2 + NADPH
?
-
-
-
-
?
3-methylphenol + O2 + NADPH
?
3-nitrophenol + NADPH + H+ + O2
?
-
about 45% of the activity with phenol
-
-
?
4-aminophenol + O2 + NADPH
?
4-bromophenol + NADPH + H+ + O2
4-bromocatechol + NADP+ + H2O
-
-
-
-
?
4-chloro-3-fluorophenol + O2 + NADPH
?
-
-
-
-
?
4-chlorocatechol + O2 + NADPH
?
-
-
-
-
?
4-chlorophenol + NADH + H+ + O2
1,2-dihydroxy-4-methylbenzene + NAD+ + H2O
4-chlorophenol + NADH + H+ + O2
4-chlorocatechol + NAD+ + H2O
4-chlorophenol + NADPH + H+ + O2
4-chlorocatechol + NADP+ + H2O
-
-
-
-
?
4-chlorophenol + NADPH + H+ + O2
? + NADP+ + H2O
-
28.6% activity compared to phenol
-
-
?
4-chlorophenol + O2 + NADPH
?
4-cresol + NADPH + H+ + O2
4-methylcatechol + NADP+ + H2O
4-cresol + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
4-cresol + NADPH + O2
4-methylcatechol + NADP+ + H2O
-
best substrate
-
-
?
4-ethylphenol + NADH + H+ + O2
4-ethylcatechol + NAD+ + H2O
4-fluorophenol + NADH + H+ + O2
1,2-dihydroxy-4-fluorobenzene + NAD+ + H2O
-
-
-
-
?
4-fluorophenol + O2 + NADPH
?
-
-
-
-
?
4-hydroxybenzaldehyde + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
4-hydroxybenzoate + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
4-hydroxybenzoic acid + NADPH + H+ + O2
? + NADP+ + H2O
-
14.88% activity compared to phenol
-
-
?
4-hydroxyindole + NADPH + O2
?
-
-
-
-
?
4-hydroxyphenol + NADPH + H+ + O2
?
-
about 120% of the activity with phenol
-
-
?
4-hydroxyphenol + O2 + NADPH
?
-
-
-
-
?
4-methoxyindole + NADPH + O2
?
-
substrate only of strain KL28
-
-
?
4-methyl-phenol + O2 + NADPH
?
4-methylindole + NADPH + O2
?
-
substrate only of strain KL28
-
-
?
4-methylphenol + NADH + H+ + O2
1,2-dihydroxy-4-methylbenzene + NAD+ + H2O
-
-
-
-
?
4-nitrophenol + NADPH + H+ + O2
4-nitrocatechol + NADP+ + H2O
-
-
-
-
?
4-nitrophenol + NADPH + H+ + O2
?
-
about 50% of the activity with phenol
-
-
?
4-propylphenol + NADH + H+ + O2
4-propylcatechol + NAD+ + H2O
5-aminoindole + NADPH + O2
?
-
-
-
-
?
5-fluoroindole + NADPH + O2
?
-
substrate only of strain KL33
-
-
?
5-hydroxyindole + NADPH + O2
?
-
-
-
-
?
5-methoxyindole + NADPH + O2
?
-
-
-
-
?
5-methylindole + NADPH + O2
?
-
substrate only of strain KL33
-
-
?
6-chloroindole + NADPH + O2
?
-
substrate only of strain KL33
-
-
?
6-methoxyindole + NADPH + O2
?
-
-
-
-
?
6-methylindole + NADPH + O2
?
-
substrate only of strain KL33
-
-
?
7-chloroindole + NADPH + O2
?
-
substrate only of strain KL33
-
-
?
7-methylindole + NADPH + O2
?
-
-
-
-
?
benzene + NADPH + H+ + O2
phenol + NADP+
-
-
-
-
?
benzene + NADPH + O2
?
-
26% of the activity with phenol
-
-
?
benzene + NADPH + O2 + H+
phenol + NADP+ + H2O
catechol + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
dibenzofuran + NADPH + H+ + O2
1,2-dihydroxydibenzofuran + NADP+ + H2O
-
-
-
-
?
hydroquinone + NADPH + H+ + O2
? + NADP+ + H2O
-
48.25% activity compared to phenol
-
-
?
indole + NADPH + O2
7-hydroxyindole + NADP+ + H2O
-
-
-
-
?
m-chlorophenol + NADPH + O2
4-chloro-benzene-1,2-diol + NADP+ + H2O
-
18% of the activity with phenol
-
-
?
m-cresol + NADH + H+ + O2
4-methylcatechol + NAD+ + H2O
m-cresol + NADPH + H+ + O2
3-methylcatechol + 4-methylcatechol + NADP+
-
-
95% 3-methylcatechol, 5% 4-methylcatechol
-
?
m-cresol + NADPH + O2
?
-
114% of the activity with phenol
-
-
?
metol + O2 + NADPH
?
-
-
-
-
?
o-chlorophenol + NADPH + O2
3-chloro-benzene-1,2-diol + NADP+ + H2O
-
20% of the activity with phenol
-
-
?
o-cresol + NADH + H+ + O2
3-methylcatechol + NAD+ + H2O
o-cresol + NADPH + O2
3-methylcatechol + NADP+ + H2O
-
37% of the activity with phenol, measured as substrate-dependent oxygen uptake rate by derivatives of Pseudomonas aeruginosa PAO1c carrying the enzyme genes after induction with phenol
-
-
?
orcinol + NADPH + O2
?
-
46% of the activity with phenol
-
-
?
oxindole + NADPH + O2
?
-
-
-
-
?
p-chlorophenol + NADPH + O2
?
-
84% of the activity with phenol
-
-
?
p-cresol + NADH + H+ + O2
4-methylcatechol + NAD+ + H2O
p-cresol + NADPH + O2
4-methylcatechol + NADP+ + H2O
-
114% of the activity with phenol
-
-
?
pentafluorophenol + O2 + NADPH
?
-
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
phenol + NADPH + H+ + O2
catechol + NADP+
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
phenol + NADPH + O2
?
-
enzyme of phenol degradation pathway
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
phloroglucinol + O2 + NADPH
?
quinol + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
quinol + NADPH + O2
?
-
63% of the activity with phenol
-
-
?
quinol + O2 + NADPH
1,2,4-trihydroxybenzene + NADP+ + H2O
resorcinol + NADPH + H+ + O2
? + NADP+ + H2O
-
-
-
-
?
resorcinol + NADPH + O2
?
thiophenol + O2 + NADPH
?
-
-
-
-
?
toluene + NADPH + H+ + O2
o-cresol + m-cresol + p-cresol + NADP+
-
-
48% o-cresol, 11% m-cresol, 41% p-cresol
-
?
toluene + NADPH + O2
?
-
28% of the activity with phenol
-
-
?
various phenolic substrates + NADPH + H+ + O2
?
-
-
-
-
?
additional information
?
-
2 2-xylene + 2 NADPH + 2 H+ + 2 O2
2,3-dimethylphenol + 3,4-dimethylphenol + 2 NADP+ + 2 H2O
-
-
-
-
?
2 2-xylene + 2 NADPH + 2 H+ + 2 O2
2,3-dimethylphenol + 3,4-dimethylphenol + 2 NADP+ + 2 H2O
-
-
-
-
?
2 ethynylbenzene + NADPH + 3 O2
2-ethynylphenol + 2-hydroxy-6-oxo-octa-2,4-dien-7-ynoic acid + NADP+ + H2O
-
-
product identification by GC-MS
-
?
2 ethynylbenzene + NADPH + 3 O2
2-ethynylphenol + 2-hydroxy-6-oxo-octa-2,4-dien-7-ynoic acid + NADP+ + H2O
-
substrate only for phenol-grown cells
-
-
?
2 ethynylbenzene + NADPH + 3 O2
2-ethynylphenol + 2-hydroxy-6-oxo-octa-2,4-dien-7-ynoic acid + NADP+ + H2O
-
-
product identification by GC-MS
-
?
2 ethynylbenzene + NADPH + 3 O2
2-ethynylphenol + 2-hydroxy-6-oxo-octa-2,4-dien-7-ynoic acid + NADP+ + H2O
-
substrate only for phenol-grown cells
-
-
?
2,4-dichlorophenol + NADPH + H+ + O2
2,4-dichlorocatechol + NADP+ + H2O
-
-
-
-
?
2,4-dichlorophenol + NADPH + H+ + O2
2,4-dichlorocatechol + NADP+ + H2O
-
-
-
-
?
2-aminophenol + NADPH + H+ + O2
2-aminocatechol + NADP+ + H2O
-
-
-
-
?
2-aminophenol + NADPH + H+ + O2
2-aminocatechol + NADP+ + H2O
-
-
-
-
?
2-aminophenol + O2 + NADPH
?
-
-
-
-
?
2-aminophenol + O2 + NADPH
?
-
-
-
-
?
2-aminophenol + O2 + NADPH
?
-
-
-
-
?
2-chlorophenol + NADPH + H+ + O2
2-chlorocatechol + NADP+ + H2O
-
-
-
-
?
2-chlorophenol + NADPH + H+ + O2
2-chlorocatechol + NADP+ + H2O
-
-
-
-
?
2-chlorophenol + O2 + NADPH
?
-
-
-
-
?
2-chlorophenol + O2 + NADPH
?
-
-
-
-
?
2-chlorophenol + O2 + NADPH
?
-
-
-
-
?
2-ethylphenol + NADPH + O2
3-ethyl-benzene-1,2-diol + NADP+ + H2O
-
18% of the activity with phenol
-
-
?
2-ethylphenol + NADPH + O2
3-ethyl-benzene-1,2-diol + NADP+ + H2O
-
18% of the activity with phenol
-
-
?
2-hydroxyphenol + NADPH + H+ + O2
?
-
about 70% of the activity with phenol
-
-
?
2-hydroxyphenol + NADPH + H+ + O2
?
-
about 70% of the activity with phenol
-
-
?
2-methyl-phenol + O2 + NADPH
?
-
i.e. o-cresol
-
-
?
2-methyl-phenol + O2 + NADPH
?
-
i.e. o-cresol
-
-
?
2-methyl-phenol + O2 + NADPH
?
-
-
-
-
?
2-nitrophenol + NADPH + H+ + O2
?
-
about 80% of the activity with phenol
-
-
?
2-nitrophenol + NADPH + H+ + O2
?
-
about 80% of the activity with phenol
-
-
?
3 toluene + 3 NADPH + 3 H+ + 3 O2
2-cresol + 3-cresol + 4-cresol + 3 NADP+ + 3 H2O
-
-
-
-
?
3 toluene + 3 NADPH + 3 H+ + 3 O2
2-cresol + 3-cresol + 4-cresol + 3 NADP+ + 3 H2O
-
-
-
-
?
3 toluene + 3 NADPH + 3 H+ + 3 O2
2-cresol + 3-cresol + 4-cresol + 3 NADP+ + 3 H2O
-
-
-
-
?
3 toluene + 3 NADPH + 3 H+ + 3 O2
2-cresol + 3-cresol + 4-cresol + 3 NADP+ + 3 H2O
-
regioselectivity, overview
-
-
?
3 toluene + 3 NADPH + 3 H+ + 3 O2
2-cresol + 3-cresol + 4-cresol + 3 NADP+ + 3 H2O
-
regioselectivity, overview
-
-
?
3 toluene + 3 NADPH + 3 H+ + 3 O2
2-cresol + 3-cresol + 4-cresol + 3 NADP+ + 3 H2O
-
-
-
-
?
3,4-dimethylphenol + NADH + H+ + O2
1,2-dihydroxy-3,4-dimethylbenzene + NAD+ + H2O
-
85% of the activity with phenol
-
-
?
3,4-dimethylphenol + NADH + H+ + O2
1,2-dihydroxy-3,4-dimethylbenzene + NAD+ + H2O
-
85% of the activity with phenol
-
-
?
3,4-dimethylphenol + NADPH + O2
?
-
72% of the activity with phenol
-
-
?
3,4-dimethylphenol + NADPH + O2
?
-
72% of the activity with phenol
-
-
?
3-aminophenol + O2 + NADPH
?
-
-
-
-
?
3-aminophenol + O2 + NADPH
?
-
-
-
-
?
3-aminophenol + O2 + NADPH
?
-
-
-
-
?
3-chlorophenol + NADH + H+ + O2
4-chlorocatechol + NAD+ + H2O
-
15% of the activity with phenol
-
-
?
3-chlorophenol + NADH + H+ + O2
4-chlorocatechol + NAD+ + H2O
-
15% of the activity with phenol
-
-
?
3-chlorophenol + O2 + NADPH
?
-
-
-
-
?
3-chlorophenol + O2 + NADPH
?
-
-
-
-
?
3-chlorophenol + O2 + NADPH
?
-
-
-
-
?
3-cresol + NADPH + H+ + O2
3-methylcatechol + NADP+ + H2O
-
-
-
-
?
3-cresol + NADPH + H+ + O2
3-methylcatechol + NADP+ + H2O
-
-
-
-
?
3-ethylphenol + NADH + H+ + O2
4-ethylcatechol + NAD+ + H2O
-
-
-
-
?
3-ethylphenol + NADH + H+ + O2
4-ethylcatechol + NAD+ + H2O
-
-
-
-
?
3-fluorophenol + O2 + NADPH
?
-
-
-
-
?
3-fluorophenol + O2 + NADPH
?
-
below pH 6.5 3-fluorophenol is preferentially hydroxylated at the C6 ortho position, at increasing pH the C2 ortho-hydroxylation becomes more predominant
-
-
?
3-hydroxyphenol + NADPH + H+ + O2
?
-
about 60% of the activity with phenol
-
-
?
3-hydroxyphenol + NADPH + H+ + O2
?
-
about 60% of the activity with phenol
-
-
?
3-methylphenol + O2 + NADPH
?
-
i.e. m-cresol
-
-
?
3-methylphenol + O2 + NADPH
?
-
i.e. m-cresol
-
-
?
3-methylphenol + O2 + NADPH
?
-
-
-
-
?
3-methylphenol + O2 + NADPH
?
-
i.e. m-cresol
-
-
?
4-aminophenol + O2 + NADPH
?
-
-
-
-
?
4-aminophenol + O2 + NADPH
?
-
-
-
-
?
4-aminophenol + O2 + NADPH
?
-
-
-
-
?
4-chlorophenol + NADH + H+ + O2
1,2-dihydroxy-4-methylbenzene + NAD+ + H2O
-
-
-
-
?
4-chlorophenol + NADH + H+ + O2
1,2-dihydroxy-4-methylbenzene + NAD+ + H2O
-
-
-
-
?
4-chlorophenol + NADH + H+ + O2
4-chlorocatechol + NAD+ + H2O
-
27% of the activity with phenol
-
-
?
4-chlorophenol + NADH + H+ + O2
4-chlorocatechol + NAD+ + H2O
-
-
-
?
4-chlorophenol + O2 + NADPH
?
-
-
-
-
?
4-chlorophenol + O2 + NADPH
?
-
-
-
-
?
4-chlorophenol + O2 + NADPH
?
-
-
-
-
?
4-cresol + NADPH + H+ + O2
4-methylcatechol + NADP+ + H2O
-
-
-
-
?
4-cresol + NADPH + H+ + O2
4-methylcatechol + NADP+ + H2O
-
-
-
-
?
4-ethylphenol + NADH + H+ + O2
4-ethylcatechol + NAD+ + H2O
-
-
-
-
?
4-ethylphenol + NADH + H+ + O2
4-ethylcatechol + NAD+ + H2O
-
-
-
-
?
4-methyl-phenol + O2 + NADPH
?
-
-
-
-
?
4-methyl-phenol + O2 + NADPH
?
-
i.e. p-cresol
-
-
?
4-methyl-phenol + O2 + NADPH
?
-
-
-
-
?
4-propylphenol + NADH + H+ + O2
4-propylcatechol + NAD+ + H2O
-
low activity
-
-
?
4-propylphenol + NADH + H+ + O2
4-propylcatechol + NAD+ + H2O
-
low activity
-
-
?
benzene + NADPH + O2 + H+
phenol + NADP+ + H2O
-
-
-
-
?
benzene + NADPH + O2 + H+
phenol + NADP+ + H2O
-
-
-
-
?
benzene + NADPH + O2 + H+
phenol + NADP+ + H2O
-
-
-
-
?
benzene + NADPH + O2 + H+
phenol + NADP+ + H2O
-
-
-
-
?
catechol + O2 + NADPH
?
-
-
-
-
?
catechol + O2 + NADPH
?
-
-
-
-
?
m-cresol + NADH + H+ + O2
4-methylcatechol + NAD+ + H2O
-
60% of the activity with phenol
-
-
?
m-cresol + NADH + H+ + O2
4-methylcatechol + NAD+ + H2O
-
-
-
-
?
m-cresol + NADH + H+ + O2
4-methylcatechol + NAD+ + H2O
-
-
-
-
?
o-cresol + NADH + H+ + O2
3-methylcatechol + NAD+ + H2O
-
60% of the activity with phenol
-
-
?
o-cresol + NADH + H+ + O2
3-methylcatechol + NAD+ + H2O
-
low activity
-
-
?
orcinol + O2 + NADPH
?
-
-
-
-
?
orcinol + O2 + NADPH
?
-
weak
-
-
?
p-cresol + NADH + H+ + O2
4-methylcatechol + NAD+ + H2O
-
60% of the activity with phenol
-
-
?
p-cresol + NADH + H+ + O2
4-methylcatechol + NAD+ + H2O
-
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
-
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
can tolerate the phenol concentration up to 6 mM, degrades phenol through catechol ortho fission pathway
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
can tolerate the phenol concentration up to 6 mM, degrades phenol through catechol ortho fission pathway
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
-
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
can tolerate the phenol concentration up to 1 mM, harbors the both ortho and meta fission pathways simultaneously
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
can tolerate the phenol concentration up to 6 mM, harbors the both ortho and meta fission pathways simultaneously
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
can tolerate the phenol concentration up to 6 mM, degrades phenol through catechol ortho fission pathway
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
can tolerate the phenol concentration up to 6 mM, degrades phenol through catechol ortho fission pathway
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
-
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
-
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
-
-
-
-
?
phenol + NAD(P)H + H+ + O2
catechol + NAD(P)+ + H2O
A5YUW2, A5YUW3, A5YUW6, A5YUY2, A5YUY5, A5YUY6, A5YUY7, A5YUZ3, A5YUZ5, A5YUZ6, A5YUZ7, A5YUZ8, A5YUZ9, A5YV00, A5YV01, A5YV02, A5YV03, A5YV04, A5YV05, A5YV06, A5YV08, A5YV10, A5YV11, A5YV12, A5YV13, A5YV14, A5YV15, A5YV16, A5YV18, A5YV19, A5YV20 phenol degradation in the activated sludge depends on the combined activity of a number of redundant species
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
activity is reduced by 84% when NADPH is replaced by NADH
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
coupling between phenol hydroxylase and toluene/o-xylene monooxygenase optimizes the use of nonhydroxylated aromatic molecules by the draining effect of phenol hydroxylase on the products of oxidation catalyzed by toluene/o-xylene monooxygenase, thus avoiding phenol accumulation
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
-
-
-
?
phenol + NADH + H+ + O2
catechol + NAD+ + H2O
-
coupling between phenol hydroxylase and toluene/o-xylene monooxygenase optimizes the use of nonhydroxylated aromatic molecules by the draining effect of phenol hydroxylase on the products of oxidation catalyzed by toluene/o-xylene monooxygenase, thus avoiding phenol accumulation
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
100% activity
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
the enzyme catalyzes the conversion of phenols to their 2-diol derivatives
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
monitoring the production of catechol in a continuous coupled assay with recombinant catechol 2,3-dioxygenase from Pseudomonas sp. OX1
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
monitoring the production of catechol in a continuous coupled assay with recombinant catechol 2,3-dioxygenase from Pseudomonas sp. OX1
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + H+ + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
cytochrome c, 2,6-dichlorophenolindophenol, potassium ferricyanide and nitro blue tetrazolium can act as electron acceptors in vitro
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
high phenol degradation activity in vivo in strain TL3, catabolic pathway overview
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
high phenol degradation activity in vivo in strain TL3, catabolic pathway overview
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
initial step in phenol-degrading pathway
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
initial step in phenol-degrading pathway
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
reaction mechanism
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + NADPH + O2
catechol + NADP+ + H2O
-
-
-
-
?
phenol + O2
?
assay at 28°C, pH 6.8-7.0, concentration of phenol diversify from 25 mg/l to 800 mg/l
-
-
?
phenol + O2
?
utilize phenol as sole carbon and energy source, concentration of phenol diversify from 25 mg/l to 1000 mg/l, assay at 28°C, pH 6.8-7.0
-
-
?
phenol + O2
?
utilize phenol as sole carbon and energy source, concentration of phenol diversify from 25 mg/l to 1000 mg/l, assay at 28°C, pH 6.8-7.0
-
-
?
phenol + O2
?
-
assay at 28°C, pH 6.8-7.0, concentration of phenol diversify from 25 mg/l to 800 mg/l
-
-
?
phloroglucinol + O2 + NADPH
?
-
-
-
-
?
phloroglucinol + O2 + NADPH
?
-
-
-
-
?
quinol + O2 + NADPH
1,2,4-trihydroxybenzene + NADP+ + H2O
-
-
-
-
?
quinol + O2 + NADPH
1,2,4-trihydroxybenzene + NADP+ + H2O
-
-
-
-
?
resorcinol + NADPH + O2
?
-
-
-
-
?
resorcinol + NADPH + O2
?
-
-
-
-
?
resorcinol + NADPH + O2
?
-
27% of the activity with phenol
-
-
?
resorcinol + NADPH + O2
?
-
27% of the activity with phenol
-
-
?
resorcinol + NADPH + O2
?
-
-
-
-
?
resorcinol + NADPH + O2
?
-
reaction mechanism
-
-
?
additional information
?
-
-
no PHO activity with p-hydroxybenzoic acid, m-hydroxybenzoic acid, 2,3-dinitrophenol, 3,4-dichlorophenol, 2,4,5-trichlorophenol, 2,2'-dihydroxybiphenyl and L-Tyr
-
-
?
additional information
?
-
-
no PHO activity with p-hydroxybenzoic acid, m-hydroxybenzoic acid, 2,3-dinitrophenol, 3,4-dichlorophenol, 2,4,5-trichlorophenol, 2,2'-dihydroxybiphenyl and L-Tyr
-
-
?
additional information
?
-
-
the enzyme has broad substrate specificity against isomeric diphenols, isomeric methylphenols, halogen-substituted phenols, amino-substituted phenols, nitrophenols, hydroxybenzaldehyde and hydroxylbenzoic acid
-
-
-
additional information
?
-
-
the enzyme has broad substrate specificity against isomeric diphenols, isomeric methylphenols, halogen-substituted phenols, amino-substituted phenols, nitrophenols, hydroxybenzaldehyde and hydroxylbenzoic acid
-
-
?
additional information
?
-
-
the enzyme has broad substrate specificity against isomeric diphenols, isomeric methylphenols, halogen-substituted phenols, amino-substituted phenols, nitrophenols, hydroxybenzaldehyde and hydroxylbenzoic acid
-
-
-
additional information
?
-
-
not: p-hydroxyphenylacetic acid
-
-
?
additional information
?
-
-
not: 2,4-, 2,5- and 2,6-dimethylphenols
-
-
?
additional information
?
-
-
not: p-hydroxybenzoic acid
-
-
?
additional information
?
-
-
not: salicylic acid
-
-
?
additional information
?
-
-
broad specificity
-
-
?
additional information
?
-
-
not: salicylic acid
-
-
?
additional information
?
-
-
broad specificity, reaction results in the formation of the corresponding o-diols
-
-
?
additional information
?
-
-
overview of possible reaction products of fluorinated phenols
-
-
?
additional information
?
-
-
first enzyme of phenol biodegradation
-
-
?
additional information
?
-
-
the enzyme hydroxylates phenol and several different toxic phenol derivatives, e.g. cresols, nitrophenols and hydroxyphenols, substrate specificity, overview
-
-
?
additional information
?
-
-
the enzyme hydroxylates phenol and several different toxic phenol derivatives, e.g. cresols, nitrophenols and hydroxyphenols, substrate specificity, overview
-
-
?
additional information
?
-
-
phenol degradation pathway, overview
-
-
?
additional information
?
-
-
the enzyme is a hydrocarbon-oxidizing multicomponent monooxygenase, important for activity is formation of a complex between the hydroxylase and a regulatory protein component
-
-
?
additional information
?
-
-
the enzyme is a multicomponent phenol hydroxylase, production of dyes from indole derivatives by recombinant enzymes expressed in Escherichia coli, substrate specificities of the enzyme from strain KL28 and KL33, the products formed by the enzyme from the two strain are different, detailed overview
-
-
?
additional information
?
-
-
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
-
-
?
additional information
?
-
-
only complete enzyme systems containing all three or four protein components are capable of oxidizing phenol. The electron-transfer components exert regulatory effects on substrate oxidation processes taking place at the hydroxylase actives sites, most likely through allostery. The regulatory proteins facilitate the electron-transfer step in the hydrocarbon oxidation cycle in the absence of phenol. Under these conditions, electron consumption is coupled to H2O2 formation in a hydroxylase-dependent manner
-
-
?
additional information
?
-
-
the enzyme is a hydrocarbon-oxidizing multicomponent monooxygenase, important for activity is formation of a complex between the hydroxylase and a regulatory protein component
-
-
?
additional information
?
-
-
the enzyme hydroxylates benzenes to catechols via the intermediate production of phenols
-
-
?
additional information
?
-
-
the enzyme hydroxylates benzenes to catechols via the intermediate production of phenols
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Krug, M.; Straube, G.
Degradation of phenolic compounds by the yeast Candida tropicalis HP 15. II. Some properties of the first two enzymes of the degradation pathway
J. Basic Microbiol.
26
271-281
1986
Candida tropicalis
brenda
Neujahr, H.Y.; Gaal, A.
Phenol hydroxylase from yeast. Purification and properties of the enzyme from Trichosporon cutaneum
Eur. J. Biochem.
35
386-400
1973
Cutaneotrichosporon cutaneum
brenda
Nakagawa, H.; Takeda, Y.
Phenol hydroxylase
Biochim. Biophys. Acta
62
423-426
1962
Brevibacterium fuscum
brenda
Neujahr, H.Y.; Gaal, A.
Phenol hydroxylase from yeast. Sulfhydryl groups in phenol hydroxylase from Trichosporon cutaneum
Eur. J. Biochem.
58
351-357
1975
Cutaneotrichosporon cutaneum
brenda
Kjellen, K.G.; Neujahr, H.Y.
Immobilization of phenol hydroxylase
Biotechnol. Bioeng.
21
715-719
1979
Cutaneotrichosporon cutaneum
brenda
Detmer, K.; Massey, V.
Effect of monovalent anions on the mechanism of phenol hydroxylase
J. Biol. Chem.
259
11265-11272
1984
Cutaneotrichosporon cutaneum
brenda
Detmer, K.; Massey, V.
Effect of substrate and pH on the oxidative half-reaction of phenol hydroxylase
J. Biol. Chem.
260
5998-6005
1985
Cutaneotrichosporon cutaneum
brenda
Neujahr, H.Y.; Kjellen, K.G.
Phenol hydroxylase from yeast. Reaction with phenol derivatives
J. Biol. Chem.
253
8835-8841
1978
Cutaneotrichosporon cutaneum
brenda
Neujahr, H.Y.
Effect of anions, chaotropes, and phenol on the attachment of flavin adenine dinucleotide to phenol hydroxylase
Biochemistry
22
580-584
1983
Cutaneotrichosporon cutaneum
brenda
Neujahr, H.Y.; Kjellen, K.G.
Phenol hydroxylase from yeast: a lysyl residue essential for binding of reduced nicotinamide adenine dinucleotide phosphate
Biochemistry
19
4967-4972
1980
Cutaneotrichosporon cutaneum
brenda
Selitz, T.; Neujahr, H.Y.
Phenol hydroxylase from yeast. A model for phenol binding and an improved purification procedure
Eur. J. Biochem.
170
343-349
1987
Cutaneotrichosporon cutaneum
brenda
Mrtberg, M.; Neujahr, H.Y.
In situ and in vitro kinetics of phenol hydroxylase
Biochem. Biophys. Res. Commun.
146
41-46
1987
Cutaneotrichosporon cutaneum
brenda
Cadieux, E.; Vrajmasu, V.; Achim, C.; Powlowski, J.; Muenck, E.
Biochemical, Mossbauer, and EPR studies of the diiron cluster of phenol hydroxylase from Pseudomonas sp. strain CF 600
Biochemistry
41
10680-10691
2002
Pseudomonas sp., Pseudomonas sp. CF 600
brenda
Enroth, C.; Neujahr, H.; Schneider, G.; Lindqvist, Y.
The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis
Structure
6
605-617
1998
Cutaneotrichosporon cutaneum
brenda
Hino, S.; Watanabe, K.; Takahashi, N.
Phenol hydroxylase cloned from Ralstonia eutropha strain E2 exhibits novel kinetic properties
Microbiology
144
1765-1772
1998
Cupriavidus necator, Cupriavidus necator E2
-
brenda
Kaelin, M.; Neujahr, H.Y.; Weissmahr, R.N.; Sejlitz, T.; Joehl, R.; Fiechter, A.; Reiser, J.
Phenol hydroxylase from Trichosporon cutaneum: gene cloning, sequence analysis, and functional expression in Escherichia coli
J. Bacteriol.
174
7112-7120
1992
Cutaneotrichosporon cutaneum
brenda
Maeda-Yorita, K.; Massey, V.
On the reaction mechanism of phenol hydroxylase. New information obtained by correlation of fluorescence and absorbance stopped flow studies
J. Biol. Chem.
268
4134-4144
1993
Cutaneotrichosporon cutaneum
brenda
Peelen, S.; Rietjens, I.M.C.M.; Boersma, M.G.; Vervoort, J.
Conversion of phenol derivatives to hydroxylated products by phenol hydroxylase from Trichosporon cutaneum. A comparison of regioselectivity and rate of conversion with calculated molecular orbital substrate characteristics
Eur. J. Biochem.
227
284-291
1995
Cutaneotrichosporon cutaneum
brenda
Peelen, S.; Rietjens, I.M.C.M.; van Berkel, W.J.H.; van Workum, W.A.T.; Vervoort, J.
Fluorine-19 NMR study on the pH-dependent regioselectivity and rate of the ortho-hydroxylation of 3-fluorophenol by phenol hydroxylase from Trichosporon cutaneum. Implications for the reaction mechanism
Eur. J. Biochem.
218
345-353
1993
Cutaneotrichosporon cutaneum
brenda
Pessione, E.; Divari, S.; Griva, E.; Cavaletto, M.; Rossi, G.L.; Gilardi, G.; Giunta, C.
Phenol hydroxylase from Acinetobacter radioresistens is a multicomponent enzyme. Purification and characterization of the reductase moiety
Eur. J. Biochem.
265
549-555
1999
Acinetobacter radioresistens
brenda
Waters, S.; Neujahr, H.Y.
A fermentor culture for production of recombinant phenol hydroxylase
Protein Expr. Purif.
5
534-540
1994
Cutaneotrichosporon cutaneum
brenda
Waters, S.; Neujahr, H.Y.
Sources and nature of heterogeneity in recombinant phenol hydroxylase derived from the basidiomycetous soil yeast Trichosporon cutaneum
Biotechnol. Appl. Biochem.
25
235-242
1997
Cutaneotrichosporon cutaneum
-
brenda
Xu, D.; Ballou, D.P.; Massey, V.
Studies of the mechanism of phenol hydroxylase: mutants Tyr289Phe, Asp54Asn, and Arg281Met
Biochemistry
40
12369-12378
2001
Cutaneotrichosporon cutaneum
brenda
Xu, D.; Enroth, C.; Lindqvist, Y.; Ballou, D.P.; Massey, V.
Studies of the mechanism of phenol hydroxylase: Effect of mutation of proline 364 to serine
Biochemistry
41
13627-13636
2002
Cutaneotrichosporon cutaneum
brenda
Enroth, C.
High-resolution structure of phenol hydroxylase and correction of sequence errors
Acta Crystallogr. Sect. D
59
1597-1602
2003
Cutaneotrichosporon cutaneum
brenda
Cafaro, V.; Izzo, V.; Scognamiglio, R.; Notomista, E.; Capasso, P.; Casbarra, A.; Pucci, P.; Di Donato, A.
Phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas stutzeri OX1: interplay between two enzymes
Appl. Environ. Microbiol.
70
2211-2219
2004
Pseudomonas stutzeri, Pseudomonas stutzeri OX1
brenda
Alexievaa, Z.; Gerginova, M.; Zlateva, P.; Peneva, N.
Comparison of growth kinetics and phenol metabolizing enzymes of Trichosporon cutaneum R57 and mutants with modified degradation abilities
Enzyme Microb. Technol.
34
242-247
2004
Cutaneotrichosporon cutaneum
-
brenda
Griva, E.; Pessione, E.; Divari, S.; Valetti, F.; Cavaletto, M.; Rossi, G.L.; Giunta, C.
Phenol hydroxylase from Acinetobacter radioresistens S13. Isolation and characterization of the regulatory component
Eur. J. Biochem.
270
1434-1440
2003
Acinetobacter radioresistens, Acinetobacter radioresistens S13
brenda
Divari, S.; Valetti, F.; Caposio, P.; Pessione, E.; Cavaletto, M.; Griva, E.; Gribaudo, G.; Gilardi, G.; Giunta, C.
The oxygenase component of phenol hydroxylase from Acinetobacter radioresistens S13
Eur. J. Biochem.
270
2244-2253
2003
Acinetobacter radioresistens, Acinetobacter radioresistens S13
brenda
Stiborova, M.; Sucha, V.; Miksanova, M.; Paca, J.Jr.; Paca, J.
Hydroxylation of phenol to catechol by Candida tropicalis: involvement of cytochrome P450
Gen. Physiol. Biophys.
22
167-179
2003
Candida tropicalis
brenda
Jeong, J.J.; Kim, J.H.; Kim, C.K.; Hwang, I.; Lee, K.
3- and 4-alkylphenol degradation pathway in Pseudomonas sp. strain KL28: genetic organization of the lap gene cluster and substrate specificities of phenol hydroxylase and catechol 2,3-dioxygenase
Microbiology
149
3265-3277
2003
Pseudomonas sp., Pseudomonas sp. KL28
brenda
Ahuatzi-Chacon, D.; Ordorica-Morales, G.; Ruiz-Ordaz, N.; Cristiani-Urbina, E.; Juarez-Ramirez, C.; Galindez-Mayer, J.
Kinetic study of phenol hydroxylase and catechol 1,2-dioxygenase dioxygenase biosynthesis by Candida tropicalis cells grown on different phenolic substrates.
World J. Microbiol. Biotechnol.
20
695-702
2004
Candida tropicalis
brenda
Teramoto, M.; Futamata, H.; Harayama, S.; Watanabe, K.
Characterization of a high-affinity phenol hydroxylase from Comamonas testosteroni R5 by gene cloning, and expression in Pseudomonas aeruginosa PAO1c
Mol. Gen. Genet.
262
552-558
1999
Comamonas testosteroni, Comamonas testosteroni R5
brenda
Cafaro, V.; Notomista, E.; Capasso, P.; Di Donato, A.
Regiospecificity of two multicomponent monooxygenases from Pseudomonas stutzeri OX1: molecular basis for catabolic adaptation of this microorganism to methylated aromatic compounds
Appl. Environ. Microbiol.
71
4736-4743
2005
Pseudomonas stutzeri, Pseudomonas stutzeri OX1
brenda
Cafaro, V.; Notomista, E.; Capasso, P.; Di Donato, A.
Mutation of glutamic acid 103 of toluene o-xylene monooxygenase as a means to control the catabolic efficiency of a recombinant upper pathway for degradation of methylated aromatic compounds
Appl. Environ. Microbiol.
71
4744-4750
2005
Pseudomonas stutzeri, Pseudomonas stutzeri OX1
brenda
Kagle, J.; Hay, A.G.
Phenylacetylene reversibly inhibits the phenol hydroxylase of Pseudomonas sp. CF600 at high concentrations but is oxidized at lower concentrations
Appl. Microbiol. Biotechnol.
72
306-315
2006
Pseudomonas sp., Pseudomonas sp. CF 600
brenda
Merimaa, M.; Heinaru, E.; Liivak, M.; Vedler, E.; Heinaru, A.
Grouping of phenol hydroxylase and catechol 2,3-dioxygenase genes among phenol- and p-cresol-degrading Pseudomonas species and biotypes
Arch. Microbiol.
186
287-296
2006
Pseudomonas sp.
brenda
Sazinsky, M.H.; Dunten, P.W.; McCormick, M.S.; Didonato, A.; Lippard, S.J.
X-ray structure of a hydroxylase-regulatory protein complex from a hydrocarbon-oxidizing multicomponent monooxygenase, Pseudomonas sp. OX1 phenol hydroxylase
Biochemistry
45
15392-15404
2006
Pseudomonas sp., Pseudomonas sp. OX1
brenda
Tsai, S.C.; Tsai, L.D.; Li, Y.K.
An isolated Candida albicans TL3 capable of degrading phenol at large concentration
Biosci. Biotechnol. Biochem.
69
2358-2367
2005
Candida albicans, Candida albicans TL3
brenda
Kim, J.Y.; Kim, J.K.; Lee, S.O.; Kim, C.K.; Lee, K.
Multicomponent phenol hydroxylase-catalysed formation of hydroxyindoles and dyestuffs from indole and its derivatives
Lett. Appl. Microbiol.
41
163-168
2005
Pseudomonas sp.
brenda
Viggor, S.; Heinaru, E.; Kuennapas, A.; Heinaru, A.
Evaluation of different phenol hydroxylase-possessing phenol-degrading pseudomonads by kinetic parameters
Biodegradation
19
759-769
2008
Pseudomonas putida, Pseudomonas fluorescens, Pseudomonas mendocina
brenda
Gerginova, M.; Manasiev, J.; Shivarova, N.; Alexieva, Z.
Influence of various phenolic compounds on phenol hydroxylase activity of a Trichosporon cutaneum strain
Z. Naturforsch. C
62
83-86
2007
Cutaneotrichosporon cutaneum, Cutaneotrichosporon cutaneum R57
brenda
Manasiev, J.; Gerginova, M.; Yemendzhiev, H.; Peneva, N.; Alexieva, Z.
Molecular analysis of phenol-degrading microbial strains
Z. Naturforsch. C
63
133-138
2008
no activity in Escherichia coli, no activity in Lactobacillus acidophilus, Cutaneotrichosporon cutaneum, no activity in Escherichia coli JM109
brenda
Zhu, C.; Zhang, L.; Zhao, L.
Molecular cloning, genetic organization of gene cluster encoding phenol hydroxylase and catechol 2,3-dioxygenase in Alcaligenes faecalis IS-46
World J. Microbiol. Biotechnol.
24
1687-1695
2008
Alcaligenes faecalis, Alcaligenes faecalis (A5HMH6), Alcaligenes faecalis (A5HMH7), Alcaligenes faecalis (A5HMH8), Alcaligenes faecalis (A5HMH9), Alcaligenes faecalis (A5HMI0), Alcaligenes faecalis (A5HMI1), Alcaligenes sp. IS-46 (Q6V9W5), Alcaligenes faecalis IS-67, Alcaligenes faecalis IS-46 (A5HMH6), Alcaligenes faecalis IS-46 (A5HMH7), Alcaligenes faecalis IS-46 (A5HMH8), Alcaligenes faecalis IS-46 (A5HMH9), Alcaligenes faecalis IS-46 (A5HMI0), Alcaligenes faecalis IS-46 (A5HMI1)
brenda
Basile, L.A.; Erijman, L.
Quantitative assessment of phenol hydroxylase diversity in bioreactors using a functional gene analysis
Appl. Microbiol. Biotechnol.
78
863-872
2008
uncultured microorganism (A5YUW2), uncultured microorganism (A5YUW3), uncultured microorganism (A5YUW6), uncultured microorganism (A5YUY2), uncultured microorganism (A5YUY5), uncultured microorganism (A5YUY6), uncultured microorganism (A5YUY7), uncultured microorganism (A5YUZ3), uncultured microorganism (A5YUZ5), uncultured microorganism (A5YUZ6), uncultured microorganism (A5YUZ7), uncultured microorganism (A5YUZ8), uncultured microorganism (A5YUZ9), uncultured microorganism (A5YV00), uncultured microorganism (A5YV01), uncultured microorganism (A5YV02), uncultured microorganism (A5YV03), uncultured microorganism (A5YV04), uncultured microorganism (A5YV05), uncultured microorganism (A5YV06), uncultured microorganism (A5YV08), uncultured microorganism (A5YV10), uncultured microorganism (A5YV11), uncultured microorganism (A5YV12), uncultured microorganism (A5YV13), uncultured microorganism (A5YV14), uncultured microorganism (A5YV15), uncultured microorganism (A5YV16), uncultured microorganism (A5YV18), uncultured microorganism (A5YV19), uncultured microorganism (A5YV20)
brenda
Zhan, Y.; Yu, H.; Yan, Y.; Ping, S.; Lu, W.; Zhang, W.; Chen, M.; Lin, M.
Benzoate catabolite repression of the phenol degradation in Acinetobacter calcoaceticus PHEA-2
Curr. Microbiol.
59
368-373
2009
Acinetobacter calcoaceticus
brenda
Nebe, J.; Baldwin, B.; Kassab, R.; Nies, L.; Nakatsu, C.
Quantification of aromatic oxygenase genes to evaluate enhanced bioremediation by oxygen releasing materials at a gasoline-contaminated site
Environ. Sci. Technol.
43
2029-2034
2009
uncultured microorganism
brenda
Dong, X.; Hong, Q.; He, L.; Jiang, X.; Li, S.
Characterization of phenol-degrading bacterial strains isolated from natural soil
Int. Biodeter. Biodegrad.
62
257-262
2008
Acinetobacter sp. PND-4 (A5Z0R4), Acinetobacter sp. PND-5 (A5Z0R5), Pseudomonas sp. PND-1 (A7L9S7), Pseudomonas sp. PND-2 (A7L9S8), Comamonas sp. PND-3 (A7L9S9), Cupriavidus sp. PND-6 (A7L9T0)
-
brenda
Yemendzhiev, H.; Gerginova, M.; Krastanov, A.; Stoilova, I.; Alexieva, Z.
Growth of Trametes versicolor on phenol
J. Ind. Microbiol. Biotechnol.
35
1309-1312
2008
Trametes versicolor, Trametes versicolor 1
brenda
Izzo, V.; Leo, G.; Scognamiglio, R.; Troncone, L.; Birolo, L.; Di Donato, A.
PHK from phenol hydroxylase of Pseudomonas sp. OX1. Insight into the role of an accessory protein in bacterial multicomponent monooxygenases
Arch. Biochem. Biophys.
505
48-59
2011
Pseudomonas sp., Pseudomonas sp. OX1
brenda
Ma, F.; Shi, S.N.; Sun, T.H.; Li, A.; Zhou, J.T.; Qu, Y.Y.
Biotransformation of benzene and toluene to catechols by phenol hydroxylase from Arthrobacter sp. W1
Appl. Microbiol. Biotechnol.
97
5097-5103
2013
Arthrobacter sp.
brenda
McCormick, M.S.; Lippard, S.J.
Analysis of substrate access to active sites in bacterial multicomponent monooxygenase hydroxylases: X-ray crystal structure of xenon-pressurized phenol hydroxylase from Pseudomonas sp. OX1
Biochemistry
50
11058-11069
2011
Pseudomonas sp., Pseudomonas sp. OX1
brenda
Tinberg, C.E.; Song, W.J.; Izzo, V.; Lippard, S.J.
Multiple roles of component proteins in bacterial multicomponent monooxygenases: phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas sp. OX1
Biochemistry
50
1788-1798
2011
Pseudomonas sp., Pseudomonas sp. OX1
brenda
Turek, M.; Vilimkova, L.; Kremlackova, V.; Paca Jr., J.; Halecky, M.; Paca, J.; Stiborova, M.
Isolation and partial characterization of extracellular NADPH-dependent phenol hydroxylase oxidizing phenol to catechol in Comamonas testosteroni
Neuroendocrinol. Lett.
32
137-145
2011
Comamonas testosteroni
brenda
Szoekoel, J.; Rucka, L.; Simcikova, M.; Halada, P.; Nesvera, J.; Patek, M.
Induction and carbon catabolite repression of phenol degradation genes in Rhodococcus erythropolis and Rhodococcus jostii
Appl. Microbiol. Biotechnol.
98
8267-8279
2014
Rhodococcus erythropolis, Rhodococcus jostii, Rhodococcus erythropolis CCM2595
brenda
Shi, S.; Qu, Y.; Tan, L.; Ma, F.
Biosynthesis of 1,2-dihydroxydibenzofuran by magnetically immobilized cells of Escherichia coli expressing phenol hydroxylase in liquid-liquid biphasic systems
Biores. Technol.
197
72-78
2015
Arthrobacter sp. W1
brenda
Long, Y.; Yang, S.; Xie, Z.; Cheng, L.
Identification and characterization of phenol hydroxylase from phenol-degrading Candida tropicalis strain JH8
Can. J. Microbiol.
60
585-591
2014
Candida tropicalis, Candida tropicalis JH8
brenda
Das, B.; Patra, S.
Multisubstrate specific flavin containing monooxygenase from Chlorella pyrenoidosa with potential application for phenolic wastewater remediation and biosensor application
Environ. Technol.
39
2073-2089
2017
Auxenochlorella pyrenoidosa
brenda
Shi, S.; Ma, F.; Sun, T.; Li, A.; Zhou, J.; Qu, Y.
Multistep conversion of cresols by phenol hydroxylase and 2,3-dihydroxy-biphenyl 1,2-dioxygenase
Front. Environ. Sci. Eng.
8
539-546
2014
Pseudomonas sp., Pseudomonas sp. OX1
-
brenda
Xiao, X.; Si, M.; Yang, Z.; Zhang, Y.; Guan, J.; Chaudhry, M.T.; Wang, Y.; Shen, X.
Molecular characterization of a eukaryotic-like phenol hydroxylase from Corynebacterium glutamicum
J. Gen. Appl. Microbiol.
61
99-107
2015
Corynebacterium glutamicum
brenda
El-Sayed, W.S.; Ibrahim, M.K.; Ouf, S.A.
Molecular characterization of the alpha subunit of multicomponent phenol hydroxylase from 4-chlorophenol-degrading Pseudomonas sp. strain PT3
J. Microbiol.
52
13-19
2014
Pseudomonas sp. PT3 (A0A060N2T5)
brenda
Das, B.; Patra, S.
Multisubstrate specific flavin containing monooxygenase from Chlorella pyrenoidosa with potential application for phenolic wastewater remediation and biosensor application
Environ. Technol.
39
2073-2089
2018
Auxenochlorella pyrenoidosa, Auxenochlorella pyrenoidosa NCIM 2738
brenda