1.1.1.362: aklaviketone reductase
This is an abbreviated version!
For detailed information about aklaviketone reductase, go to the full flat file.
Reaction
Synonyms
DauE
ECTree
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Systematic Name
Systematic Name on EC 1.1.1.362 - aklaviketone reductase
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aklavinone:NADP+ oxidoreductase
The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin.