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1.1.1.B38: hydroxymethylglutaryl-CoA reductase [NAD(P)H]

This is an abbreviated version!
For detailed information about hydroxymethylglutaryl-CoA reductase [NAD(P)H], go to the full flat file.

Word Map on EC 1.1.1.B38

Reaction

mevalonate
+
CoA
+ 2 NAD(P)+ =
3-hydroxy-3-methylglutaryl-CoA
+ 2 NAD(P)H + 2 H+

Synonyms

3-hydroxy-3-methylglutaryl coenzyme A reductase, AF1736, class II HMG-CoA reductase, HGMR, HMG-CoA reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B38 hydroxymethylglutaryl-CoA reductase [NAD(P)H]

Crystallization

Crystallization on EC 1.1.1.B38 - hydroxymethylglutaryl-CoA reductase [NAD(P)H]

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
enzyme bound to 3-hydroxy-3-methylglutaryl-CoA, hanging drop vapor diffusion method, using 100 mM Tris pH 8.5, 100-250 mM lithium sulfate, and 15-25% (w/v) PEG 4000. Enzyme bound to NADPH, hanging drop vapor diffusion method, using 100 mM Tris pH 8.5, 100-250 mM lithium sulfate, and 30-40% (w/v) PEG 4000
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