1.14.11.63: peptidyl-lysine (3S)-dioxygenase

This is an abbreviated version!
For detailed information about peptidyl-lysine (3S)-dioxygenase, go to the full flat file.

Reaction

Synonyms

JmjC domain-containing protein 7, JMJD7, Jumonji domain-containing protein 7

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

                1.14.11.63 peptidyl-lysine (3S)-dioxygenase

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Results	in table
4	AA Sequence
1	Application
1	Cloned(Commentary)
1	Crystallization (Commentary)
4	General Information
7	IC50 Value
7	Inhibitors
2	Localization
2	Natural Substrates/ Products (Substrates)
6	Organism
1	Protein Variants
1	Reaction
6	Reference
1	Source Tissue
6	Substrates and Products (Substrate)
9	Synonyms
1	Systematic Name

IC50 Value

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IC50 Value on EC 1.14.11.63 - peptidyl-lysine (3S)-dioxygenase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0072

2-[(3-fluoro-3'-methoxy[1,1'-biphenyl]-4-yl)carbamoyl]cyclopent-1-ene-1-carboxylic acid

Homo sapiens

P0C872

pH not specified in the publication, temperature not specified in the publication

764299

-

0.0332

2-[3-(3,4-dimethoxyphenyl)propanamido]benzoic acid

Homo sapiens

P0C872

pH not specified in the publication, temperature not specified in the publication

764299

-

0.0501

3-amino-N-[3-(4-amino-4-methylcyclohexyl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]-2,3-dihydropyrazine-2-carboxamide

Homo sapiens

P0C872

pH not specified in the publication, temperature not specified in the publication

764299

-

0.011

5-(1,3-benzothiazol-2-yl)-N-propylthiophene-2-carboxamide

Homo sapiens

P0C872

pH not specified in the publication, temperature not specified in the publication

764299

-

0.0316

7-[phenyl[(pyridin-2-yl)amino]methyl]quinolin-8-ol

Homo sapiens

P0C872

pH not specified in the publication, temperature not specified in the publication

764299

0.0282

ethyl 2-[[(4-nitrophenyl)methanesulfonyl]carbamoyl]pyridine-4-carboxylate

Homo sapiens

P0C872

pH not specified in the publication, temperature not specified in the publication

764299

-

0.0066

[8-[(2,4-dichlorobenzoyl)oxy]quinolin-5-yl]azinic acid

Homo sapiens

P0C872

pH not specified in the publication, temperature not specified in the publication

764299

-