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1.14.13.127: 3-(3-hydroxyphenyl)propanoate hydroxylase

This is an abbreviated version!
For detailed information about 3-(3-hydroxyphenyl)propanoate hydroxylase, go to the full flat file.

Reaction

(2E)-3-(3-hydroxyphenyl)prop-2-enoate
+
NADH
+
H+
+
O2
=
(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate
+
H2O
+
NAD+

Synonyms

3-(3-hydroxyphenyl)propionate hydroxylase, 3HPP 2-hydroxylase, 3HPP hydroxylase, MhpA, MhpAK-12

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.127 3-(3-hydroxyphenyl)propanoate hydroxylase

Reference

Reference on EC 1.14.13.127 - 3-(3-hydroxyphenyl)propanoate hydroxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Burlingame, R.; Chapmen, P.J.
Catabolism of phenylpropionic acid and its 3-hydroxy-derivative by Escherichia coli
J. Bacteriol.
155
113-121
1983
Escherichia coli, Escherichia coli KK334
Manually annotated by BRENDA team
Burlingame, R.P.; Wyman, L.; Chapman, P.J.
Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation
J. Bacteriol.
168
55-64
1986
no activity in Escherichia coli, no activity in Escherichia coli LW303, no activity in Escherichia coli LW279
Manually annotated by BRENDA team
Diaz, E.; Ferrandez, A.; Garcia, J.L.
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12
J. Bacteriol.
180
2915-2923
1998
Escherichia coli
Manually annotated by BRENDA team
Ferrandez, A.; Garcia, J.L.; Diaz, E.
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12
J. Bacteriol.
179
2573-2581
1997
Escherichia coli
Manually annotated by BRENDA team
Arai, H.; Yamamoto, T.; Ohishi, T.; Shimizu, T.; Nakata, T.; Kudo, T.
Genetic organization and characteristics of the 3-(3-hydroxyphenyl)propionic acid degradation pathway of Comamonas testosteroni TA441
Microbiology
145
2813-2820
1999
Comamonas testosteroni, Comamonas testosteroni TA441
Manually annotated by BRENDA team
Xu, Y.; Zhou, N.Y.
MhpA is a hydroxylase catalyzing the initial reaction of 3-(3-hydroxyphenyl)propionate catabolism in Escherichia coli K-12
Appl. Environ. Microbiol.
86
e02385-19
2020
Escherichia coli (P77397), Escherichia coli, Escherichia coli W3110 (P77397)
Manually annotated by BRENDA team