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1.14.14.40: phenylalanine N-monooxygenase

This is an abbreviated version!
For detailed information about phenylalanine N-monooxygenase, go to the full flat file.

Word Map on EC 1.14.14.40

Reaction

L-phenylalanine
+ 2 [reduced NADPH-hemoprotein reductase] + 2 O2 =
(E)-phenylacetaldoxime
+ 2 [oxidized NADPH-hemoprotein reductase] +
CO2
+ 3 H2O

Synonyms

CYP79A1, CYP79A2, CYP79D16, cytochrome P450 79D16, EC 1.14.13.124

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.40 phenylalanine N-monooxygenase

pH Range

pH Range on EC 1.14.14.40 - phenylalanine N-monooxygenase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6
25% of maximum activity
6 - 7.9
compared with the activity at pH 7.5, the activity of chimeric CYP79A2 is 25% at pH 6.0, 50% at pH 6.5, 80% at pH 7.0, and 70% at pH 7.9
7.9
70% of maximum activity