1.2.1.42: hexadecanal dehydrogenase (acylating)

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For detailed information about hexadecanal dehydrogenase (acylating), go to the full flat file.

Reaction

Synonyms

ACIAD3383, Acr1, AtFAR2, CoA-acylating aldehyde dehydrogenase, coenzyme A-acylating aldehyde dehydrogenase, dehydrogenase, hexadecanal (acylating), FACoAR, FAR, FAR1, FAR2, FAR6, fatty acid reductase, fatty acyl-CoA reductase, MS2, PduP

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.42 hexadecanal dehydrogenase (acylating)

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Results	in table
8	Activating Compound
12	AA Sequence
1	CAS Registry Number
14	Cloned(Commentary)
16	Cofactor
3	General Information
2	Inhibitors
2	kcat/KM [mM/s]
13	KM Value [mM]
7	Localization
9	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
21	Organism
1	Oxidation Stability
8	pH Optimum
3	pH Range
6	Protein Variants
7	Purification (Commentary)
2	Reaction
3	Reaction Type
21	Reference
6	Source Tissue
13	Specific Activity [micromol/min/mg]
58	Substrates and Products (Substrate)
8	Subunits
31	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Stability [°C]
2	Turnover Number [1/s]

General Information

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General Information on EC 1.2.1.42 - hexadecanal dehydrogenase (acylating)

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

evolution

Arabidopsis thaliana

Q08891

AtFAR2 is highly similar in properties and substrate specificity to AtFAR6

741502

malfunction

Arabidopsis thaliana

Q08891

mutations in specific genes encoding fatty acid reductases (FAR) re­sponsible for fatty alcohol production cause abnormal development of pollen. A disrupted AtFAR2 (MS2) gene in Arabidopsis thaliana results in pollen developing an abnormal exine layer and a reduced fertility pheno­type

741502

physiological function

Arabidopsis thaliana

Q08891

AtFAR2 is a fatty acid reductase from Arabidopsis thaliana that reduces fatty acyl-CoA and -ACP substrates into fatty alcohols, cf. EC 1.2.1.80. Enzyme AtFAR2 is the major enzyme respon­sible for exine layer functionality, AtFAR6 might provide functional redundancy to AtFAR2

741502