1.2.1.61: 4-hydroxymuconic-semialdehyde dehydrogenase

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For detailed information about 4-hydroxymuconic-semialdehyde dehydrogenase, go to the full flat file.

Reaction

Synonyms

4-HS dehydrogenase, 4-hydroxymuconic semialdehyde dehydrogenase, gamma-hydroxymuconic semialdehyde dehydrogenase, hAPE, HqdC, NAD dependent gamma-hydroxymuconic semialdehyde dehydrogenase, PdcG, pnpE

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.61 4-hydroxymuconic-semialdehyde dehydrogenase

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Results

in table

5

AA Sequence

2

Application

3

Cloned(Commentary)

4

Cofactor

1

Crystallization (Commentary)

9

Engineering

2

Expression

6

General Information

2

Inhibitors

12

Metals/Ions

3

Molecular Weight [Da]

2

Natural Substrates/ Products (Substrates)

16

Organism

4

Pathway

2

pH Optimum

1

pH Range

1

pH Stability

2

Purification (Commentary)

2

Reaction

3

Reaction Type

8

Reference

1

Source Tissue

4

Specific Activity [micromol/min/mg]

8

Substrates and Products (Substrate)

1

Subunits

19

Synonyms

1

Systematic Name

2

Temperature Optimum [�C]

1

Temperature Range [�C]

1

Temperature Stability [�C]

Reaction

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Reaction on EC 1.2.1.61 - 4-hydroxymuconic-semialdehyde dehydrogenase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

4-hydroxymuconic semialdehyde + NAD+ + H2O = maleylacetate + NADH + H+

2 entries

4-hydroxymuconic semialdehyde + NAD+ + H2O = maleylacetate + NADH + H+

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4-hydroxymuconic semialdehyde + NAD+ + H2O = maleylacetate + NADH + H+

catalytic mechanism involving residues Glu247 and Cys281

Pseudomonas sp. WBC-3

C1I208

742206