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1.2.7.10: oxalate oxidoreductase

This is an abbreviated version!
For detailed information about oxalate oxidoreductase, go to the full flat file.

Word Map on EC 1.2.7.10

Reaction

oxalate
+
oxidized ferredoxin
= 2 CO2 +
reduced ferredoxin

Synonyms

Moth_1591, Moth_1592, Moth_1593, OOR

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.7 With an iron-sulfur protein as acceptor
                1.2.7.10 oxalate oxidoreductase

General Information

General Information on EC 1.2.7.10 - oxalate oxidoreductase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
CoA has no effect on catalysis by OOR. OOR binds pyruvate and catalyzes decarboxylation to form the same hydroxyethylidine-thiamine diphosphate intermediate and one-electron transfer to generate the hydroxyethylidine-thiamine diphosphate radical as does pyruvate:ferredoxin oxidoreductase, EC 1.2.7.1. In OOR, this intermediate remains stranded at the active site as a covalent inhibitor. OOR generates an oxalate-derived adduct with thiamine diphosphate (oxalyl-TPP) that undergoes decarboxylation and one-electron transfer to form a radical intermediate remaining bound to thiamine diphosphate