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1.3.8.8: long-chain acyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about long-chain acyl-CoA dehydrogenase, go to the full flat file.

Word Map on EC 1.3.8.8

Reaction

a long-chain acyl-CoA
+
electron-transfer flavoprotein
=
a long-chain trans-2,3-dehydroacyl-CoA
 +
reduced electron-transfer flavoprotein

Synonyms

ACAD 9, AcdB, acyl-CoA dehydrogenase 9, BACH, CTE-II, EC 1.3.99.13, EC 1.3.99.3, LCAD, long chain acyl coenzyme A dehydrogenase, long chain acyl-CoA dehydrogenase, long-chain acyl-CoA dehydrogenase, long-chain acyl-CoA hydrolase, long-chain acyl-coenzyme A dehydrogenase, MCAD, medium long-chain acyl-CoA dehydrogenase, More, MTE-II, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, PtmO4, type-II acyl-CoA thioesterase, very long chain acyl-CoA dehydrogenase, very long-chain acyl-CoA dehydrogenase, very-long-chain acyl-CoA dehydrogenase, very-long-chain acyl-coenzyme A dehydrogenase, VLCAD, VLMCAD

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.8 long-chain acyl-CoA dehydrogenase

Specific Activity

Specific Activity on EC 1.3.8.8 - long-chain acyl-CoA dehydrogenase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00034
-
crude extract, strain TH183, genotype fadR251(S), acetate and oleate as carbon source
0.00052
-
crude extract, strain TH18, genotype fadR251(S), acetate as carbon source
0.00064
-
crude extract, strain TH182, genotype fadR250(S) acetate as carbon source
0.00083
-
crude extract, strain TH182, genotype fadR250(S), acetate and oleate as carbon source
0.0011
-
crude extract, strain TH181, genotype fadR+, acetate as carbon source
0.00238
-
MCAD activity, controls
0.0038
-
crude extract, strain TH181, genotype fadR+, acetate and oleate as carbon source
0.0046
-
crude extract, strain RS3010, genotype fadR1, acetate as carbon source
0.0055
-
crude extract, strain RS3010, genotype fadR1, acetate and oleate as carbon source
0.00695
-
VLCAD activity, controls, range 0.00195 to 0.01191
0.01241
-
fibroblast homogenates, palmitoyl-CoA
0.06
-
purified holoenzyme, arachidonoyl-CoA
0.06037
-
LCAD enzyme activity in livers of partially deficient LCAD mice 8 weeks after injection of recombinant adeno-associated viral mLCAD vector via the hepatic portal vein
0.076
-
purified enzyme, butyryl-CoA
0.19
-
purified enzyme, palmitoyl-CoA, 0.12 nmol/ml ETF
0.2546
-
LCAD enzyme activity in tibialis anterior muscle of LCAD-heterozygous deficient mice 10 weeks post-injection 1 x 10exp11 vg recombinant adeno-associated viral mLCAD
0.259
-
purified enzyme, palmitoyl-CoA, 0.24 nmol/ml ETF
0.27
-
purified enzyme, (R/S)-2-methylpalmitoyl-CoA
0.272
-
purified enzyme, octanoyl-CoA
0.3
-
purified holoenzyme, docosanoyl-CoA
0.34
-
purified enzyme, (S)-2-methylpentadecanoyl-CoA
0.38
-
purified holoenzyme, linolenoyl-CoA
0.39
-
purified enzyme, palmitoyl-CoA
0.7
-
purified holoenzyme, octanoyl-CoA
0.72
-
purified holoenzyme, linoleoyl-CoA
0.8
-
purified enzyme, decanoyl-CoA
0.82
-
purified enzyme, palmitoyl-CoA
0.9
-
purified holoenzyme, eicosanoyl-CoA
1.13
-
purified holoenzyme, oleoyl-CoA
1.48
-
purified apoenzyme, palmitoyl-CoA
1.51
-
purified holoenzyme, palmitoleoyl-CoA
1.52
-
purified apoenzyme, palmitoyl-CoA
1.6
-
purified holoenzyme, stearoyl-CoA
1.8
-
purified holoenzyme, dodecanoyl-CoA
1.96
-
purified holoenzyme, palmitoyl-CoA
15.27
-
purified enzyme, decanoyl-CoA
2.1
-
purified holoenzyme, tetradecanoyl-CoA
32.5
-
purified enzyme, decanoyl-CoA
additional information