1.3.99.4: 3-oxosteroid 1-dehydrogenase

This is an abbreviated version!
For detailed information about 3-oxosteroid 1-dehydrogenase, go to the full flat file.

Word Map on EC 1.3.99.4

1.3.99.4

rhodococcus

3-ketosteroids

mycobacterium

cholesterol

4-androstene-3,17-dione

erythropolis

synthesis

arthrobacter

simplex

isoenzymes

testosteroni

rhodochrous

androst-4-ene-3,17-dione

bioconversion

hydrocortisone

dehydrogenation

phytosterols

ruber

steroid-transforming

globiformis

1,4-androstadiene-3,17-dione

neoaurum

molecular biology

Reaction

Synonyms

1-ene-dehydrogenase, 3-keto-5alpha-steroid DELTA(1)-dehydrogenase, 3-ketosteroid 1(2)-dehydrogenase, 3-ketosteroid delta1-dehydrogenase, 3-ketosteroid-1-en-dehydrogenase, 3-ketosteroid-D1-dehydrogenase, 3-ketosteroid-DELTA1-dehydrogenase, 3-ketosteroid-DELTA1-dehydrogenases, 3-oxosteroid D1-dehydrogenase, 3-oxosteroid Delta1-dehydrogenase, 3-oxosteroid:(2,6-dichlorphenolindophenol) DELTA1-oxidoreductase, 3-oxosteroid:(2,6-dichlorphenolindophenol)D1-oxidoreductase, 4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase, 4-ene-3-oxosteroid: (acceptor)-1-ene-oxoreductase, 4-ene-3-oxosteroid:(acceptor)l-ene-oxidoreductase, AcmB, AcmB2, cholest-4-en-3-one DELTA1-dehydrogenase, D1-dehydrogenase, D1-steroid reductase, dehydrogenase, 3-oxo steroid Delta 1-, Delta1-dehydrogenase, DELTA1-KstD, DELTA1-KSTD1, DELTA1-KstDA, DELTA1-KstDR, DELTA1-steroid reductase, ketosteroid DELTA1-dehydrogenase, KsdD, KsdD1, KsdD2, KsdD3, KsdD5, KsdDM, KSDH, KstD, KSTD1, KSTD2, KSTD3, KSTD3 orthologue, KstDF, MnKstD1, MnKstD2, MsKstD1, MsKstD2, MsKstD3, MsKstD4, ReKstD1, Rv3537, steroid-1-dehydrogenase

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.99 With unknown physiological acceptors

1.3.99.4 3-oxosteroid 1-dehydrogenase

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Results	in table
11	Activating Compound
1430	AA Sequence
20	Application
1	CAS Registry Number
36	Cloned(Commentary)
24	Cofactor
2	Crystallization (Commentary)
4	Expression
42	General Information
5	General Stability
42	Inhibitors
45	kcat/KM [mM/s]
135	KM Value [mM]
9	Localization
9	Metals/Ions
10	Molecular Weight [Da]
65	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
547	Organism
8	Pathway
18	PDB ID
24	pH Optimum
4	pH Range
5	pH Stability
3	pI Value
58	Protein Variants
19	Purification (Commentary)
4	Reaction
3	Reaction Type
107	Reference
31	Specific Activity [micromol/min/mg]
4	Storage Stability
341	Substrates and Products (Substrate)
32	Subunits
232	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
3	Temperature Range [°C]
10	Temperature Stability [°C]
56	Turnover Number [1/s]

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50.2 - 2842.34

11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione

3 entries

20.3 - 6825.77

11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione acetate

3 entries

13849.8

16,17alpha-epoxyprogesterone

Mycolicibacterium neoaurum

A0A2P1IUZ5

recombinant enzyme, pH 8.0, 40°C

762659

45.4 - 103.1

17-methyl-testosterone

2 entries

126.1 - 8452.5

17alpha,21-dihydroxyprogesterone 21-acetate

2 entries

21.4 - 9929.5

17alpha-hydroxypregn-4-ene-3,20-dione

3 entries

92.8

17alpha-hydroxyprogesterone

Pimelobacter simplex

pH 7.5, 35°C, recombinant isozyme KsdD3

763180

13.7 - 26.9

21-acetoxy-pregna-4,9(11),16-triene-3,20-dinone

2 entries

12.8 - 63.5

21-chloro-17-hydroxy-pregna-4,9(11)-diene-3,20-dione

2 entries

40.8 - 94.1

4-androsten-3-one-5-ene-17-carboxylic acid

2 entries

0.036 - 9625.36

4-androstene-3,17-dione

11 entries

5.8 - 27.8

4-Cholesten-3-one

2 entries

21.4 - 1862.9

9alpha-hydroxy-4-androstene-3,17-dione

3 entries

10.2 - 22.3

androst-4,9(11)-diene-3,17-dione

2 entries

6475.3

androsta-4,9(11)-diene-3,17-dione

Mycolicibacterium neoaurum

A0A2P1IUZ5

recombinant enzyme, pH 8.0, 40°C

762659

95.8 - 2774.12

canrenone

2 entries

20.6 - 94.2

cortexolone

2 entries

24.6 - 52.2

cortisone

2 entries

67.4

cortisone acetate

Pimelobacter simplex

pH 7.5, 35°C, recombinant isozyme KsdD3

763180

14.4

pregna-4,9(11),16-triene-3,20-dione

Mycolicibacterium smegmatis

A0QW99, A0R1T2, A0R1T7

pH 8.0, 25°C

762654

15.7 - 127.8

progesterone

4 entries

24.7 - 77.5

testosterone

4 entries