1.5.3.21: 4-methylaminobutanoate oxidase (methylamine-forming)
This is an abbreviated version!
For detailed information about 4-methylaminobutanoate oxidase (methylamine-forming), go to the full flat file.
Reaction
Synonyms
MAO
ECTree
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11 | AA Sequence |
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2 | Molecular Weight [Da] |
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5 | Pathway |
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General Information
General Information on EC 1.5.3.21 - 4-methylaminobutanoate oxidase (methylamine-forming)
for references in articles please use BRENDA:EC1.5.3.21
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physiological function
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in nicotine breakdown, two alternative pathways for the final steps in the catabolism of 4-methylaminobutanoate could be identified. 4-Methylaminobutanoate may be demethylated to gamma-N-aminobutyrate by gamma-N-methylaminobutanoate oxidase, EC 1.5.3.19. In an alternative pathway, amine oxidase, EC 1.5.3.21, removes methylamine from 4-methylaminobutanoate with the formation of succinic semialdehyde. Kinetic analyses suggest that demethylation predominates over deamination of 4-methylaminobutanoate