1.7.1.7: GMP reductase

This is an abbreviated version!
For detailed information about GMP reductase, go to the full flat file.

Word Map on EC 1.7.1.7

1.7.1.7

purine

imp

salvage

hypoxanthine

impdhs

hypoxanthine-guanine

adenylosuccinate

medicine

drug development

Reaction

Synonyms

EC 1.6.6.8, GMPR, GMPR-I, GMPR-II, GMPR2, guaC, Guanosine 5'-monophosphate oxidoreductase, guanosine 5'-monophosphate reductase, guanosine monophosphate reductase, guanosine monophosphate reductase 2, guanosine-5'-monophosphate reductase, guanylate reductase, HsGMPR1, HsGMPR2, LmGMPR, Lmj17.0725, LMJF_17_0725, NADPH:GMP oxidoreductase (deaminating), reductase, guanylate, Tb927.5.2080, TbGMPR, TcGMPR, TCIL3000_5_1940

ECTree

1 Oxidoreductases

1.7 Acting on other nitrogenous compounds as donors

1.7.1 With NAD⁺ or NADP⁺ as acceptor

1.7.1.7 GMP reductase

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Results	in table
10	Activating Compound
9196	AA Sequence
3	Application
1	CAS Registry Number
13	Cloned(Commentary)
27	Cofactor
3	Crystallization (Commentary)
45	Disease/ Diagnostics
1	Expression
13	General Information
1	General Stability
4	IC50 Value
75	Inhibitors
2	kcat/KM [mM/s]
10	Ki Value [mM]
40	KM Value [mM]
5	Localization
9	Metals/Ions
16	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
46	Organism
4	Pathway
32	PDB ID
12	pH Optimum
4	pH Range
1	pI Value
1	Posttranslational Modification
5	Protein Variants
14	Purification (Commentary)
6	Reaction
4	Reaction Type
40	Reference
44	Source Tissue
16	Specific Activity [micromol/min/mg]
5	Storage Stability
48	Substrates and Products (Substrate)
10	Subunits
53	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
4	Turnover Number [1/s]

Purification

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Purification on EC 1.7.1.7 - GMP reductase

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4 entries

affinity purification on Cibacron blue

Homo sapiens

394287

from recombinant COS-7 cells

Homo sapiens

Q9P2T1

659550

Ni Sepharose 6 column chromatography and Sephacryl S-200HR gel filtration

Trypanosoma brucei

765448

Ni-NTA agarose resin column chromatography

partial

recombinant enzyme using His-tag

Homo sapiens

657445

recombinant GST-tagged enzyme from Escherichia coli strain BL21 (DE3) by glutathione affinity chromatography, the tag is cleaved off by a commercial protease, followed by dialysis

Trypanosoma brucei brucei

Q57ZS7

743568

recombinant His-tagged enzyme

Homo sapiens

Q9P2T1

394294

recombinant untagged enzyme from Escherichia coli strain H1174 by affinity chromatography

Leishmania major

Q4QEB3

743300