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1.8.1.6: cystine reductase

This is an abbreviated version!
For detailed information about cystine reductase, go to the full flat file.

Word Map on EC 1.8.1.6

Reaction

2 L-cysteine +

NAD+
=
L-cystine
 +
NADH
 +
H+

Synonyms

CydDC, CysR, cystine reductase (NADH), cystine reductase (NADH2), EC 1.6.4.1, L-cysteine:NAD+ oxidoreductase, L-cystine reductase, NADH-dependent cystine reductase, NADH2:L-cystine oxidoreductase, reductase, cystine, thioredoxin domain containing 17, thioredoxin-like 5, TRP14, TXNDC17, TXNL5

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.6 cystine reductase

Disease

topprint

Disease on EC 1.8.1.6 - cystine reductase

Please use the Disease Search for a specific query.
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Bone Resorption
TRP14 inhibits osteoclast differentiation via its catalytic activity.
Colorectal Neoplasms
Retraction notice to "STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells" [GENE 584 (1) (2016) 75-82].
STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells.
Decompression Sickness
Dynorphin-phospholipid membrane interactions: role of phospholipid head-group and cholesterol.
Hypersensitivity
CydDC functions as a cytoplasmic cystine reductase to sensitize Escherichia coli to oxidative stress and aminoglycosides.
Isogenic mutations in the Moraxella catarrhalis CydDC system display pleiotropic phenotypes and reveal the role of a palindrome sequence in its transcriptional regulation.
Infections
The CydDC Family of Transporters and Their Roles in Oxidase Assembly and Homeostasis.
The CydDC family of transporters.
Neoplasms
Dynein light chain LC8 negatively regulates NF-kappaB through the redox-dependent interaction with IkappaBalpha.
Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways.
Suberoylanilide hydroxamic acid sensitizes neuroblastoma to paclitaxel by inhibiting thioredoxin-related protein 14-mediated autophagy.
Thioredoxin-related protein 14, a new member of the thioredoxin family with disulfide reductase activity: Implication in the redox regulation of TNF-alpha signaling.
TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer.
Neuroblastoma
Suberoylanilide hydroxamic acid sensitizes neuroblastoma to paclitaxel by inhibiting thioredoxin-related protein 14-mediated autophagy.
Ovarian Neoplasms
TRP14 promotes resistance to cisplatin by inducing autophagy in ovarian cancer.
TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer.