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EC 2.7.8.14 Details

show Brenda entry

EC number

2.7.8.14

Accepted name

CDP-ribitol ribitolphosphotransferase

Reaction

n CDP-ribitol + 4-O-di[(2R)-1-glycerophospho]-N-acetyl-β-D-mannosaminyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = n CMP + 4-O-(D-ribitylphospho)_n-di[(2R)-1-glycerophospho]-N-acetyl-β-D-mannosaminyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol

Other name(s)

teichoic-acid synthase (ambiguous), polyribitol phosphate synthetase (ambiguous), teichoate synthetase (ambiguous), poly(ribitol phosphate) synthetase (ambiguous), polyribitol phosphate polymerase (ambiguous), teichoate synthase (ambiguous), CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase

Systematic name

CDP-ribitol:4-O-di[(2R)-1-glycerophospho]-N-acetyl-β-D-mannosaminyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol ribitolphosphotransferase

CAS registry number

9076-71-5

Comment

Involved in the biosynthesis of poly ribitol phosphate teichoic acids in the cell wall of the bacterium Staphylococcus aureus. This enzyme adds around 40 ribitol units to the linker molecule.

History

created 1972 as EC 2.4.1.55, transferred 1982 to EC 2.7.8.14, modified 2017

EC Tree

1 Oxidoreductases

2 Transferases

2.1 Transferring one-carbon groups

2.2 Transferring aldehyde or ketonic groups

2.3 Acyltransferases

2.4 Glycosyltransferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.6 Transferring nitrogenous groups

2.7 Transferring phosphorus-containing groups

2.8 Transferring sulfur-containing groups

2.8.1 Sulfurtransferases

2.8.1.1 thiosulfate sulfurtransferase

2.8.1.2 3-mercaptopyruvate sulfurtransferase

2.8.1.3 thiosulfate—thiol sulfurtransferase

2.8.1.4 tRNA uracil 4-sulfurtransferase

2.8.1.5 thiosulfate—dithiol sulfurtransferase

2.8.1.6 biotin synthase

2.8.1.7 cysteine desulfurase

2.8.1.8 lipoyl synthase

2.8.1.9 molybdenum cofactor sulfurtransferase

2.8.1.10 thiazole synthase

2.8.1.11 molybdopterin synthase sulfurtransferase

2.8.1.12 molybdopterin synthase

2.8.1.13 tRNA-uridine 2-sulfurtransferase

2.8.1.14 tRNA-5-taurinomethyluridine 2-sulfurtransferase

2.8.1.15 tRNA-5-methyluridine⁵⁴ 2-sulfurtransferase

2.8.1.16 L-aspartate semialdehyde sulfurtransferase

2.8.2 Sulfotransferases

2.8.3 CoA-transferases

2.8.3.1 propionate CoA-transferase

2.8.3.2 oxalate CoA-transferase

2.8.3.3 malonate CoA-transferase

2.8.3.4 created 1961, deleted 1964

2.8.3.5 3-oxoacid CoA-transferase

2.8.3.6 3-oxoadipate CoA-transferase

2.8.3.7 succinate—citramalate CoA-transferase

2.8.3.8 acetate CoA-transferase

2.8.3.9 butyrate—acetoacetate CoA-transferase

2.8.3.10 citrate CoA-transferase

2.8.3.11 citramalate CoA-transferase

2.8.3.12 glutaconate CoA-transferase

2.8.3.13 succinate—hydroxymethylglutarate CoA-transferase

2.8.3.14 5-hydroxypentanoate CoA-transferase

2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase

2.8.3.16 formyl-CoA transferase

2.8.3.17 3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase

2.8.3.18 succinyl-CoA:acetate CoA-transferase

2.8.3.19 CoA:oxalate CoA-transferase

2.8.3.20 succinyl-CoA—D-citramalate CoA-transferase

2.8.3.21 L-carnitine CoA-transferase

2.8.3.22 succinyl-CoA—L-malate CoA-transferase

2.8.3.23 caffeate CoA-transferase

2.8.3.24 (R)-2-hydroxy-4-methylpentanoate CoA-transferase

2.8.3.25 bile acid CoA-transferase

2.8.3.26 succinyl-CoA:mesaconate CoA transferase

2.8.3.27 propanoyl-CoA:succinate CoA transferase

2.8.3.28 phenylsuccinyl-CoA transferase

2.8.4 Transferring alkylthio groups

2.8.5 Thiosulfotransferases

2.9 Transferring selenium-containing groups

2.10 Transferring molybdenum- or tungsten-containing groups