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EC 2.8.1.13 Details
EC number
2.8.1.13
Accepted name
tRNA-uridine 2-sulfurtransferase
Reaction
a [protein]-S-sulfanyl-L-cysteine + uracil34 in tRNA + ATP + reduced acceptor = a [protein]-L-cysteine + 2-thiouracil34 in tRNA + AMP + diphosphate + acceptor
Other name(s)
mnmA (gene name)
Systematic name
[protein]-S-sulfanyl-L-cysteine:tRNA (uracil34-2-O)-sulfurtransferase
Comment
The enzyme, found in bacteria, catalyses formation of the 2-thiouridine modification in the wobble position of tRNAGln, tRNALys and tRNAGlu.
History
created 2015
EC Tree
2.8.3.4 created 1961, deleted 1964