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EC 4.3.2.3 Details

show Brenda entry

EC number

4.3.2.3

Accepted name

ureidoglycolate lyase

Reaction

(S)-ureidoglycolate = glyoxylate + urea

Other name(s)

ureidoglycolatase (ambiguous), ureidoglycolase (ambiguous), ureidoglycolate hydrolase (misleading), (S)-ureidoglycolate urea-lyase

Systematic name

(S)-ureidoglycolate urea-lyase (glyoxylate-forming)

CAS registry number

9014-57-7

Comment

This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 3.5.1.116, ureidoglycolate amidohydrolase, which releases ammonia rather than urea.

History

created 1972, modified 2014

EC Tree

4.1 Carbon-carbon lyases

4.2 Carbon-oxygen lyases

4.3 Carbon-nitrogen lyases

4.3.1 Ammonia-lyases

4.3.2 Amidine-lyases

4.3.2.1 argininosuccinate lyase

4.3.2.2 adenylosuccinate lyase

4.3.2.3 ureidoglycolate lyase

4.3.2.4 purine imidazole-ring cyclase

4.3.2.5 peptidylamidoglycolate lyase

4.3.2.6 γ-L-glutamyl-butirosin B γ-glutamyl cyclotransferase

4.3.2.7 glutathione-specific γ-glutamylcyclotransferase

4.3.2.8 γ-glutamylamine cyclotransferase

4.3.2.9 γ-glutamylcyclotransferase

4.3.2.10 imidazole glycerol-phosphate synthase

4.3.2.11 (3R)-3-[(carboxylmethyl)amino]fatty acid synthase

4.3.3 Amine-lyases

4.3.3.1 3-ketovalidoxylamine C-N-lyase

4.3.3.2 strictosidine synthase

4.3.3.3 deacetylisoipecoside synthase

4.3.3.4 deacetylipecoside synthase

4.3.3.5 4′-demethylrebeccamycin synthase

4.3.3.6 pyridoxal 5′-phosphate synthase (glutamine hydrolysing)

4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase

4.3.99 Other carbon-nitrogen lyases

4.4 Carbon-sulfur lyases

4.5 Carbon-halide lyases

4.6 Phosphorus-oxygen lyases

4.7 carbon-phosphorus lyases

4.8 Nitrogen-oxygen lyases

4.98 ATP-independent chelatases