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EC 4.3.2.11 Details
EC number
4.3.2.11
Accepted name
(3R)-3-[(carboxylmethyl)amino]fatty acid synthase
Reaction
(3R)-3-[(carboxylmethyl)amino]fatty acid + an [acyl-carrier protein] = a (2E)-unsaturated fatty acyl-[acyl-carrier protein] + glycine + H2O
Other name(s)
scoD (gene name), mmaD (gene name)
Systematic name
(3R)-3-[(carboxylmethyl)amino]fatty acid glycine-lyase ((2E)-unsaturated fatty acyl-[acyl-carrier protein]-forming)
Comment
The enzyme, found in some actinobacterial species, participates in the biosynthesis of isonitrile-containing lipopeptides. It catalyses the formation of (3R)-3-[(carboxylmethyl)amino]fatty acid by the addition of glycine and the release of the product from the acyl-carrier protein.
History
created 2022